https://www.atsjournals.org/doi/abs/10.1164/ajrccm.2025.211.Abstracts.A7881
Exercise Pathophysiology in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and Long COVID: Commonalities Detected by Invasive Cardiopulmonary Exercise Testing
J. Squires 1, S. Palwayi 1, P. Li 3, W. Xiao 3, K...
ME/CFS Pathophysiology Investigated by Invasive Cardiopulmonary Exercise Testing and Autonomic Function Testing.
J. Squires 2, K. Wichmann Madsen 2, M.C. Stovall 2, S. Al-Zayer 2, W. Xiao 3, C.-J. Chang 3, P. Novak 1, D.M. Systrom 2...
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We have four threads, one for each day of the conference. Please add the following to these threads:
* reports from forum members attending the conference
* tweets and reports from other social media
* your thoughts about the information presented.
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Post has been moved from the "United Kingdom: ME Association news" thread
Mitochondrial dysfunction in Long Covid and ME/CFS
David Systrom, a pulmonary and critical care doctor at Brigham & Women’s Hospital, Boston, believes he has found answers through studying patients with ME/CFS, an...
ABSTRACT
Background
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is characterized by intractable fatigue, post-exertional malaise, and orthostatic intolerance, but its pathophysiology is poorly understood. Pharmacologic cholinergic stimulation was used to test the hypothesis that...
Via a Solve M.E. e-bulletin
RECOVER Seminar: Commonalities with Other Disorders and Post-viral Syndromes,
Focus on ME/CFS
As part of the RECOVER Research Review (R3) Seminar Series, there will be a panel discussion titled, "Commonalities with Other Disorders and Post-viral Syndromes: Focus on...
Abstract
Background
Some Coronavirus disease 2019 (COVID-19) patients who have recovered from their acute infection after experiencing only mild symptoms continue to exhibit persistent exertional limitation that is often unexplained by conventional investigative studies.
Research question
What...
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Brief Summary:
Myalgic encephalomyelitis/Chronic fatigue syndrome (ME/CFS), otherwise known as Chronic fatigue syndrome (CFS) or myalgic encephalomyelitis (ME), is an under-recognized disorder whose cause is not yet understood. Suggested theories behind the pathophysiology of this condition...
European Journal of Applied Physiology:
Unexplained exertional intolerance associated with impaired systemic oxygen extraction
by Kathryn H. Melamed, Mário Santos, Rudolf K. F. Oliveira, Mariana Faria Urbina, Donna Felsenstein, Alexander R. Opotowsky, Aaron B. Waxman, David M. Systrom
Abstract...
There are a number of references to chronic fatigue syndrome in this paper, including in the abstract, so I thought I would post it here, particularly given that Systrom is a co-author. He is now doing some ME/CFS research in the US.
Free full text...
Dr. David M. Systrom of Brigham and Women’s Hospital (Boston) is confident that his team has objective evidence of small-fiber polyneuropathy (SFPN) in 40-50% of ME patients.
Dr Systrom was interviewed by Llewelyn King in this video: . I put the timestamp at the part involved with SFPN but the...
American Journal of Respiratory and Critical Care Medicine 2018;197:A6146
Exercise Intolerance in Preload Failure Treated with Pyridostigmine
M. Faria Urbina 1, R. Oliveira 2, A.L. Oaklander 3, A.B. Waxman 1, D.M. Systrom 1...
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