systrom

  1. Dolphin

    Exercise Pathophysiology in ME/CFS and Long COVID: Commonalities Detected by Invasive Cardiopulmonary Exercise Testing, 2025, Squires, Systrom et al

    https://www.atsjournals.org/doi/abs/10.1164/ajrccm.2025.211.Abstracts.A7881 Exercise Pathophysiology in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and Long COVID: Commonalities Detected by Invasive Cardiopulmonary Exercise Testing J. Squires 1, S. Palwayi 1, P. Li 3, W. Xiao 3, K...
  2. Dolphin

    Trial Report Exercise capacity in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) treated with long-term pyridostigmine, 2023, Systrom

    https://erj.ersjournals.com/content/62/suppl_67/PA4639 Exercise capacity in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) treated with long-term pyridostigmine Johanna Squires, Sarra Al-Zayer, David Systrom European Respiratory Journal 2023 62: PA4639; DOI...
  3. V

    ME/CFS Pathophysiology Investigated by Invasive Cardiopulmonary Exercise Testing and Autonomic Function Testing, 2023, Squires, ..Systrom et. al.

    ME/CFS Pathophysiology Investigated by Invasive Cardiopulmonary Exercise Testing and Autonomic Function Testing. J. Squires 2, K. Wichmann Madsen 2, M.C. Stovall 2, S. Al-Zayer 2, W. Xiao 3, C.-J. Chang 3, P. Novak 1, D.M. Systrom 2...
  4. Sasha

    USA Centers for Disease Control (CDC) news (including ME/CFS Stakeholder Engagement and Communication Calls) - next call 4 Dec 2024

    This thread includes posts on general news from the CDC and ME/CFS news including stakeholder calls. Several threads have been merged.
  5. Science For ME

    IACFSME 2022 Virtual Medical Conference: Day 2 Presentations: 28 July (9 am to 5 pm EDT)

    We have four threads, one for each day of the conference. Please add the following to these threads: * reports from forum members attending the conference * tweets and reports from other social media * your thoughts about the information presented. * any questions you would like asked of...
  6. John Mac

    Astellas' Bocidelpar - drug to restore mitochondrial function

    Post has been moved from the "United Kingdom: ME Association news" thread Mitochondrial dysfunction in Long Covid and ME/CFS David Systrom, a pulmonary and critical care doctor at Brigham & Women’s Hospital, Boston, believes he has found answers through studying patients with ME/CFS, an...
  7. Sly Saint

    Neurovascular Dysregulation and Acute Exercise Intolerance in ME/CFS: A Randomized, Placebo-Controlled Trial of Pyridostigmine, 2022, Systrom et al

    ABSTRACT Background Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is characterized by intractable fatigue, post-exertional malaise, and orthostatic intolerance, but its pathophysiology is poorly understood. Pharmacologic cholinergic stimulation was used to test the hypothesis that...
  8. T

    RECOVER Seminar: Commonalities with Other Disorders and Post-viral Syndromes, Focus on ME/CFS, Tuesday April 12 2022

    Via a Solve M.E. e-bulletin RECOVER Seminar: Commonalities with Other Disorders and Post-viral Syndromes, Focus on ME/CFS As part of the RECOVER Research Review (R3) Seminar Series, there will be a panel discussion titled, "Commonalities with Other Disorders and Post-viral Syndromes: Focus on...
  9. Andy

    Persistent Exertional Intolerance after COVID-19: Insights from Invasive Cardiopulmonary Exercise Testing, 2021, Singh, Systrom et al

    Abstract Background Some Coronavirus disease 2019 (COVID-19) patients who have recovered from their acute infection after experiencing only mild symptoms continue to exhibit persistent exertional limitation that is often unexplained by conventional investigative studies. Research question What...
  10. Sly Saint

    The Exercise Response to Pharmacologic Cholinergic Stimulation in ME/CFS, 2020/21, Systrom, phase2 trial registration

    " Brief Summary: Myalgic encephalomyelitis/Chronic fatigue syndrome (ME/CFS), otherwise known as Chronic fatigue syndrome (CFS) or myalgic encephalomyelitis (ME), is an under-recognized disorder whose cause is not yet understood. Suggested theories behind the pathophysiology of this condition...
  11. John Mac

    Event: Grand Rounds: Pathophysiology of Exercise Intolerance in Chronic Fatigue Syndrome Event Date: May 5th, 2020 David Systrom, MD

    https://oshercenter.org/oc-event/grand-rounds-pathophysiology-of-exercise-intolerance-in-chronic-fatigue-syndrome/
  12. Kalliope

    Unexplained exertional intolerance associated with impaired systemic oxygen extraction - 2019, by Melamed, Systrom et al

    European Journal of Applied Physiology: Unexplained exertional intolerance associated with impaired systemic oxygen extraction by Kathryn H. Melamed, Mário Santos, Rudolf K. F. Oliveira, Mariana Faria Urbina, Donna Felsenstein, Alexander R. Opotowsky, Aaron B. Waxman, David M. Systrom Abstract...
  13. Dolphin

    Fatigue, Sleep, and Autoimmune and Related Disorders, 2019, Zielinski, Systrom and Rose

    There are a number of references to chronic fatigue syndrome in this paper, including in the abstract, so I thought I would post it here, particularly given that Systrom is a co-author. He is now doing some ME/CFS research in the US. Free full text...
  14. rvallee

    David Systrom, researcher, Brigham and Women's Hospital, USA

    Dr. David M. Systrom of Brigham and Women’s Hospital (Boston) is confident that his team has objective evidence of small-fiber polyneuropathy (SFPN) in 40-50% of ME patients. Dr Systrom was interviewed by Llewelyn King in this video: . I put the timestamp at the part involved with SFPN but the...
  15. Dolphin

    Exercise Intolerance in Preload Failure Treated with Pyridostigmine (2018) Faria Urbina et al (mentions ME/CFS & POTS)

    American Journal of Respiratory and Critical Care Medicine 2018;197:A6146 Exercise Intolerance in Preload Failure Treated with Pyridostigmine M. Faria Urbina 1, R. Oliveira 2, A.L. Oaklander 3, A.B. Waxman 1, D.M. Systrom 1...
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