mitochondria

Electron-Microscopic Investigation of Muscle Mitochondria in Chronic Fatigue Syndrome Audrius V. Plioplys; Sigita Plioplys Abstract Patients with chronic fatigue syndrome (CFS) suffer from disabling physical and mental fatigue. Abnormalities in mitochondrial function can lead to fatigue and...

IFNγ causes mitochondrial dysfunction and oxidative stress in myositis Catalina Abad, Iago Pinal-Fernandez, Clement Guillou, Gwladys Bourdenet, Laurent Drouot, Pascal Cosette, Margherita Giannini, Lea Debrut, Laetitia Jean, Sophie Bernard, Damien Genty, Rachid Zoubairi, Isabelle Remy-Jouet...

Mitochondrial innate immune signaling in skeletal muscle adaptation to exercise Jin Ma; Annie Yujin Son; Youlim Son; Ping-yuan Wang; Paul M. Hwang Exercise-induced inflammation is regarded as a response to muscle damage from mechanical stress, but controlled immune signaling can be beneficial...

Indistinguishable mitochondrial phenotypes after exposure of healthy myoblasts to myalgic encephalomyelitis or control serum Audrey A. Ryback, Charles Hillier, Camila M Loureiro, Chris P Ponting, Caroline F Dalton Myalgic Encephalomyelitis (ME)/Chronic Fatigue Syndrome is a disease of...

https://www.mdpi.com/1422-0067/26/11/5339# Open Access Article Heat vs. Fatigue: Hyperthermia as a Possible Treatment Option for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) by Barbara Hochecker 1,*, Katja Matt 1, Melanie Scherer 1, Alica Meßmer 1, Alexander von Ardenne 2...

Natural polyphenol boosts mitochondrial function and muscle performance during aging I recently started taking olive leaf extract for quite different reasons before I found this, so it will be interesting to see if it has any other beneficial effects.

Regulation of synaptic mitochondria by extracellular vesicles and its implications for neuronal metabolism and synaptic plasticity Yuzhou Zeng; Anna Antoniou Mitochondrial metabolism in neurons is necessary for energetically costly processes like synaptic transmission and plasticity. As...

A human brain map of mitochondrial respiratory capacity and diversity Mosharov, Eugene V.; Rosenberg, Ayelet M.; Monzel, Anna S.; Osto, Corey A.; Stiles, Linsey; Rosoklija, Gorazd B.; Dwork, Andrew J.; Bindra, Snehal; Junker, Alex; Zhang, Ya; Fujita, Masashi; Mariani, Madeline B.; Bakalian...

Systemic Multi-Omics Analysis Reveals Interferon Response Heterogeneity and Links Lipid Metabolism to Immune Alterations in Severe COVID-19 Ronaldo Lira-Junior; Anoop Ambikan; Axel Cederholm; Ssefanit Rezene; Flora Mikaeloff; Sara Svensson Akusjarvi; Ahmet Yalcinkaya; Xi Chen; Maike Sperk...

POLG diseases: Rare genetic conditions that starve cells of energy and afflicted the late Prince of Luxembourg

Hi all! I'm a graduate student living with ME/CFS and currently studying ME/CFS and long COVID. I was recently reviewing literature on mitochondrial dysfunction and stumbled onto something very interesting which potentially explains several semi-consistent findings in the literature...

Highlights • Dengue and Zika viruses alter endoplasmic reticulum-mitochondria contact sites (ERMC) • Mitochondrial respiration is perturbed over the course of the infection • ERMC protein knockdown increases viral replication • ERMC proteins RRBP1 and SYNJ2BP regulate Zika virus-induced cell...

1H and 31P MR Spectroscopy to Assess Muscle Mitochondrial Dysfunction in Long COVID Lucy E. M. Finnigan, Mark Philip Cassar, Mehrsa Jafarpour, Antonella Sultana, Zakariye Ashkir, Karim Azer, Stefan Neubauer, Damian J. Tyler, Betty Raman, Ladislav Valkovič Background Emerging evidence suggests...

Astrocytic mitochondrial transfer to brain endothelial cells and pericytes in vivo increases with aging Gopal V Velmurugan; Hemendra J Vekaria; Samir P Patel; Patrick G Sullivan; W Brad Hubbard Intercellular mitochondrial transfer (IMT) is an intriguing biological phenomenon where mitochondria...

Good day my peeps, I would like to know if anyone has tried Red Light Therapy with a proper device (quality, third party tested etc.). If yes, what was your experience? Thank you... Low-Intensity Light Therapy: Exploring the Role of Redox Mechanisms - PMC

Cellular ATP demand creates metabolically distinct subpopulations of mitochondria Ryu, Keun Woo; Fung, Tak Shun; Baker, Daphne C.; Saoi, Michelle; Park, Jinsung; Febres-Aldana, Christopher A.; Aly, Rania G.; Cui, Ruobing; Sharma, Anurag; Fu, Yi; Jones, Olivia L.; Cai, Xin; Pasolli, H. Amalia...

Novel biomarkers of mitochondrial dysfunction in Long COVID patients Szögi, Titanilla; Borsos, Barbara N.; Masic, Dejana; Radics, Bence; Bella, Zsolt; Bánfi, Andrea; Ördög, Nóra; Zsiros, Csenge; Kiricsi, Ágnes; Pankotai-Bodó, Gabriella; Kovács, Ágnes; Paróczai, Dóra; Botkáné, Andrea Lugosi...

KEY POINTS Question: Determine the short- and long-term physical impairments and skeletal muscle cellular changes in survivors of critical COVID. Findings: Survivors of critical COVID have high prevalence of weakness, fatigue, and reduced functional exercise capacity with muscle tissue...

Editor’s summary Increased plasma creatine is associated with type 2 diabetes, but causation has not been established. Rizo-Roca et al. show that men with type 2 diabetes had increased plasma creatine and decreased muscle phosphocreatine, which was associated with poor glucose handling. In...

https://www.sciencedirect.com/science/article/abs/pii/S0960896624003353 571P Muscular metabolic plasticity in 3D in vitro models against systemic stress factors in ME/CFS and long COVID-19 Author links 1 Institute For Bioengineering Of Catalonia BIST, Barcelona, Spain 2 ICREA Institució...