microbiome

  1. DMissa

    Open Australia - Victoria: “Bottom-up”: linking the gut microbiota, immune system and metabolism in ME/CFS - Missailidis, La Trobe

    Hi everybody, I finally have the ethics in place to begin recruiting for our recently funded Mason Foundation study. ICC criteria. Healthy controls and pwME in VIC, Australia. Involves some questionaires and a blood and feces collection. We will home visit severely affected people. Primary...
  2. Dolphin

    Preprint An approach to finding specific forms of dysbiosis that associate with different disorders, 2024, Williams/Williams/Morten/Kenyon

    https://www.medrxiv.org/content/10.1101/2024.04.23.24306162v1 An approach to finding specific forms of dysbiosis that associate with different disorders Jonathan Williams, Inga Williams, Karl Morten, Julian Kenyon doi: https://doi.org/10.1101/2024.04.23.24306162 This article is a preprint...
  3. Andy

    Review Clinical evidence of the link between gut microbiome and myalgic encephalomyelitis/chronic fatigue syndrome: a retrospective review 2024 Wang et al

    Abstract Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a heterogeneous disorder with elusive causes, but most likely because of clinical and other biological factors. As a vital environmental factor, the gut microbiome is increasingly emphasized in various refractory diseases...
  4. Andy

    Viroid-like colonists of human microbiomes 2024 Zheludev et al

    Link to post with published version Preprint Abstract Here, we describe the “Obelisks,” a previously unrecognised class of viroid-like elements that we first identified in human gut metatranscriptomic data. “Obelisks” share several properties: (i) apparently circular RNA ∼1kb genome...
  5. J

    Trial Report A synbiotic preparation (SIM01) for post-acute COVID-19 syndrome in Hong Kong (RECOVERY): a randomised, double-blind, placebo-controlled tria Lau 2023

    Summary Background Post-acute COVID-19 syndrome (PACS) affects over 65 million individuals worldwide but treatment options are scarce. We aimed to assess a synbiotic preparation (SIM01) for the alleviation of PACS symptoms. Methods In this randomised, double-blind, placebo-controlled trial at a...
  6. SNT Gatchaman

    Review Studying the Human Microbiota: Advances in Understanding the Fundamentals, Origin, and Evolution of Biological Timekeeping, 2023, Siebieszuk et al.

    Studying the Human Microbiota: Advances in Understanding the Fundamentals, Origin, and Evolution of Biological Timekeeping Siebieszuk, Adam; Sejbuk, Monika; Witkowska, Anna Maria The recently observed circadian oscillations of the intestinal microbiota underscore the profound nature of the...
  7. SNT Gatchaman

    The lung microbiome regulates brain autoimmunity, 2022, Hosang et al.

    The lung microbiome regulates brain autoimmunity Hosang, Leon; Canals, Roger Cugota; van der Flier, Felicia Joy; Hollensteiner, Jacqueline; Daniel, Rolf; Flügel, Alexander; Odoardi, Francesca Lung infections and smoking are risk factors for multiple sclerosis, a T-cell-mediated autoimmune...
  8. SNT Gatchaman

    Impaired gut microbiota-mediated short-chain fatty acid production precedes morbidity and mortality in people with HIV, 2023, Sereti et al.

    Impaired gut microbiota-mediated short-chain fatty acid production precedes morbidity and mortality in people with HIV Irini Sereti; Myrthe L. Verburgh; Jacob Gifford; Alice Lo; Anders Boyd; Eveline Verheij; Aswin Verhoeven; Ferdinand W.N.M. Wit; Maarten F. Schim van der Loeff; Martin Giera...
  9. E

    Fungal microbiota sustains lasting immune activation of neutrophils and their progenitors in severe COVID-19, 2023, Iliev et al

    Fungal microbiota sustains lasting immune activation of neutrophils and their progenitors in severe COVID-19 Gastrointestinal fungal dysbiosis is a hallmark of several diseases marked by systemic immune activation. Whether persistent pathobiont colonization during immune alterations and...
  10. Joan Crawford

    Gut microbiota modulate distal symmetric polyneuropathy in patients with diabetes

    Thought this was an interesting small study. Gut microbiota modulate distal symmetric polyneuropathy in patients with diabetes Junpeng Yang 7 Xueli Yang 7 Guojun Wu 7 Faming Zhang Chenhong Zhang Huijuan Yuan 8 Open Access Published:July 13, 2023...
  11. Mij

    A germ-free humanized mouse model shows the contribution of resident microbiota to human-specific pathogen infection, 2023, Angela Wahl et al

    Abstract Germ-free (GF) mice, which are depleted of their resident microbiota, are the gold standard for exploring the role of the microbiome in health and disease; however, they are of limited value in the study of human-specific pathogens because they do not support their replication. Here...
  12. Trish

    Reduced diversity and altered composition of the gut microbiome in individuals with ME/CFS, 2016, Giloteaux, Hanson et al

    Reduced diversity and altered composition of the gut microbiome in individuals with myalgic encephalomyelitis/chronic fatigue syndrome Abstract Background Gastrointestinal disturbances are among symptoms commonly reported by individuals diagnosed with myalgic encephalomyelitis/chronic fatigue...
  13. Andy

    Longitudinal gut microbiome analyses and blooms of pathogenic strains during lupus disease flares, 2023, Azzouz et al

    Objective Whereas genetic susceptibility for systemic lupus erythematosus (SLE) has been well explored, the triggers for clinical disease flares remain elusive. To investigate relationships between microbiota community resilience and disease activity, we performed the first longitudinal...
  14. Wyva

    The Observer/Guardian article: Does the microbiome hold the key to chronic fatigue? About patient led 'research' group Remission Biome.

    Often dismissed by the medical establishment, people with complex illnesses such as ME and long Covid are taking the hunt for treatments into their own hands In 2019, years after developing the myalgic encephalomyelitis (ME/CFS) that had kept her bedridden in a state of chronic pain and...
  15. SNT Gatchaman

    Suppressed immune and metabolic responses to intestinal damage-associated microbial translocation in [ME/CFS], 2023, Uhde, Vernon et al.

    Suppressed immune and metabolic responses to intestinal damage-associated microbial translocation in myalgic encephalomyelitis/chronic fatigue syndrome Uhde; Indart; Green; Yolken; Cook; Shukla; Vernon; Alaedini The etiology and mechanism of myalgic encephalomyelitis/chronic fatigue syndrome...
  16. Sly Saint

    Causal Effects between Gut Microbiome and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Two-Sample Mendelian Randomization Study, 2023,Gang He

    The final, formatted version of the article will be published soon. Background: Evidence from previous studies have implicated an important association between gut microbiota (GM) and Myalgic Encephalomyelitis/ Chronic Fatigue Syndrome (ME/CFS), but whether there is a definite causal...
  17. Andy

    H2 generated by fermentation in the human gut microbiome influences metabolism and competitive fitness of gut butyrate producers, 2023, Campbell et al

    Background Hydrogen gas (H2) is a common product of carbohydrate fermentation in the human gut microbiome and its accumulation can modulate fermentation. Concentrations of colonic H2 vary between individuals, raising the possibility that H2 concentration may be an important factor...
  18. J

    Investigating antibody reactivity to the intestinal microbiome in severe myalgic encephalomyelitis/chronic fatigue syndrome 2023 Carding et al

    Full title: Investigating antibody reactivity to the intestinal microbiome in severe myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) Preprint Abstract Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a multisystemic disease of unknown aetiology that is characterised...
  19. Sly Saint

    Assessing the relationship between gut microbiota and irritable bowel syndrome: a two-sample Mendelian randomization analysis, 2023 Bin Liu et al

    Abstract Background Growing evidence has suggested that gut microbiota is closely related to the risk of irritable bowel syndrome (IBS), but whether there is a causal effect remains unknown. We adopted a Mendelian randomization (MR) approach to evaluate the potential causal relationships...
  20. SNT Gatchaman

    Gut Microbiota Dysbiosis Correlates With Long COVID-19 at One-Year After Discharge, 2023, Zhang et al.

    Gut Microbiota Dysbiosis Correlates With Long COVID-19 at One-Year After Discharge Zhang, Dongmei; Zhou, Yaya; Ma, Yanling; Chen, Ping; Tang, Jian; Yang, Bohan; Li, Hui; Liang, Mengyuan; Xue, YuE; Liu, Yao; Zhang, Jianchu; Wang, Xiaorong Background: Long coronavirus disease 2019 (COVID-19) in...
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