long covid

https://www.bmj.com/content/382/bmj.p1983

The β1-adrenergic receptor links sympathetic nerves to T cell exhaustion Abstract CD8+ T cells are essential components of the immune response against viral infections and tumours, and are capable of eliminating infected and cancerous cells. However, when the antigen cannot be cleared, T cells...

Severe acute respiratory syndrome coronavirus 2 infection leads to Tau pathological signature in neurons Abstract COVID-19 has represented an issue for global health since its outbreak in March 2020. It is now evident that the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)...

Early antibody treatment, inflammation, and risk of post-COVID conditions Kelly A. Gebo; Sonya L. Heath; Yuriko Fukuta; Xianming Zhu; Sheriza Baksh; Allison G. Abraham; Feben Habtehyimer; David Shade; Jessica Ruff; Malathi Ram; Oliver Laeyendecker; Reinaldo E. Fernandez; Eshan U. Patel; Owen R...

Impact of Long Covid on the school experiences of children and young people: a qualitative study Alice MacLean; Cervantee Wild; Kate Hunt; Sarah Nettleton; Zoë C Skea; Sue Ziebland Objectives To explore the impact of Long Covid (LC) on the school experiences of children and young people (CYP)...

Abstract Purpose To examine retinal and corneal neurodegenerative and retinal microvascular changes in patients after mild or asymptomatic COVID-19 disease compared to age-matched controls. Methods Thirty-five (35) patients after PCR-proven SARS-CoV-2 infection and 28 age-matched controls were...

Vaccination after developing long COVID: impact on clinical presentation, viral persistence and immune responses Maryam Nayyerabadi; Lyvia Fourcade; Swarali A. Joshi; Prabha Chandrasekaran; Arpita Chakravarti; Chantal Massé; Marie-Lorna Paul; Joanie Houle; Amina M. Boubekeur; Charlotte DuSablon...

Epstein-Barr virus-acquired immunodeficiency in myalgic encephalomyelitis-Is it present in long COVID? Abstract Both myalgic encephalomyelitis or chronic fatigue syndrome (ME/CFS) and long COVID (LC) are characterized by similar immunological alterations, persistence of chronic viral infection...

Examination of autoantibodies to type I interferon in patients suffering from long COVID Kristoffer Skaalum Hansen; Sofie Eg Jørgensen; Morten Kelder Skouboe; Jane Agergaard; Berit Schiøttz-Christensen; Line Khalidan Vibholm; Martin Tolstrup; Lars Østergaard; Steffen Leth; Trine H. Mogensen...

Exploring the mechanisms of long COVID: Insights from computational analysis of SARS-CoV-2 gene expression and symptom associations Abstract Long coronavirus disease (COVID) has emerged as a global health issue, affecting a substantial number of people worldwide. However, the underlying...

[Approx 25% of participants had LC] Background Chronic fatigue (CF) is a complex phenomenon without clear etiology that may require long-term treatment, but to date, no specific therapy has been identified for it. Some botanicals might be helpful in the management of CF. Among these botanicals...

Long-COVID cognitive impairments and reproductive hormone deficits in men may stem from GnRH neuronal death Background We have recently demonstrated a causal link between loss of gonadotropin-releasing hormone (GnRH), the master molecule regulating reproduction, and cognitive deficits during...

SARS-CoV-2 infection and long COVID among California farmworkers Ana M. Mora; Katherine Kogut; Nimrat K. Sandhu; Derry Ridgway; Chris M. Patty; Melissa Renteria; Norma Morga; Maria T. Rodriguez; Monica Romero; Jose M. Valdovinos; Alma Torres-Nguyen; Omar Guzman; Mario Martinez; Richard L. Doty...

There's just been an interview of Professor Lisa Sanders, of Diagnosis fame, who is now running the Yale Long Covid Clinic. Sunday 17 September Radio New Zealand - If I remember, I'll add a better link when it is up...

SARS-CoV-2 infection induces a long-lived pro-inflammatory transcriptional profile Zhang, Jia-Yuan; Whalley, Justin P.; Knight, Julian C.; Wicker, Linda S.; Todd, John A.; Ferreira, Ricardo C. The immune response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in...

Abstract The long-term health effects of SARS-CoV-2, termed Post-Acute Sequelae of COVID-19 (PASC), are quickly evolving into a major public health concern, but the underlying cellular and molecular etiology remain poorly defined. There is growing evidence that PASC is linked to abnormal immune...

Wasn't sure where to put this but I wanted to note the following: It's not known whether or when the ME Association plans to update its Articles of Association to reflect a change in its objectives...

Cognitive impairments and mental health of patients with post-COVID-19: A cross-sectional study Abstract Background Persistent cognitive complaints belong to the most frequent symptoms after COVID-19. This study explored the neuropsychological profile, mental healthand risk factors for...

Plasma proteomics show altered inflammatory and mitochondrial proteins in patients with neurologic symptoms of post-acute sequelae of SARS-CoV-2 infection Hanson; Visvabharathy; Orban; Jimenez; Batra; Liotta; DeLisle; Klausner; Cohen; Padhye; Tachas; Koralnik Persistent symptoms of COVID-19...

Abstract Post-COVID-19 condition, also known as long COVID-19 syndrome and post-acute sequelae of SARS-CoV-2, encompasses an array of symptoms that persist well beyond the initial phase of the viral infection. These symptoms can range in intensity, from mild and manageable to severe and...