interferon

  1. SNT Gatchaman

    An ultra-early, transient interferon-associated innate immune response associates with protection from SARS-CoV-2 infection, 2024, Fenn+

    An ultra-early, transient interferon-associated innate immune response associates with protection from SARS-CoV-2 infection despite exposure Joe Fenn et 77 al BACKGROUND A proportion of individuals exposed to respiratory viruses avoid contracting detectable infection. We tested the hypothesis...
  2. SNT Gatchaman

    [NF-κB], interferon regulatory Factor, and glucocorticoid receptor pathway activation in [depression]: The role of [CMV], 2024, Savitz+

    Nuclear factor kappa-B cell NF-κB, interferon regulatory Factor, and glucocorticoid receptor pathway activation in major depressive Disorder: The role of cytomegalovirus infection Savitz; McKinney; Meier; Zheng; Ford; Yolken; Teague; Cole Altered activity of major immunoregulatory pathways has...
  3. SNT Gatchaman

    Immune exhaustion in ME/CFS and long COVID, 2024, Eaton-Fitch et al.

    Immune exhaustion in ME/CFS and long COVID Natalie Eaton-Fitch; Penny Rudd; Teagan Er; Livia Hool; Lara Herrero; Sonya Marshall-Gradisnik Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and long COVID are debilitating multisystemic conditions sharing similarities in immune...
    • SNT Gatchaman
    • Thread
    • eaton-fitch hla hla-dqb1 ighg immune dysregulation innate immune system interferon kir marshall-gradisnik ncned
    • Replies: 12
    • Forum: ME/CFS research
  4. rvallee

    STING recognition of viral dsDNA by nociceptors mediates pain in mice, 2024, Berta et al

    STING recognition of viral dsDNA by nociceptors mediates pain in mice https://www.sciencedirect.com/science/article/pii/S0889159124004823 Highlights Nociceptors can directly sense viral nucleic acids, such as dsDNA derived from herpes and vaccinia viruses. Cytosolic dsDNA causes nocifensive...
  5. SNT Gatchaman

    Macro- and Microstructural White Matter Differences in Neurologic Postacute Sequelae of SARS-CoV-2 Infection, 2024, O’Connor et al.

    Macro- and Microstructural White Matter Differences in Neurologic Postacute Sequelae of SARS-CoV-2 Infection Erin E. O’Connor; Rosangela Salerno-Goncalves; Nikita Rednam; Rory O’Brien; Peter Rock; Andrea R. Levine; Thomas A. Zeffiro BACKGROUND AND PURPOSE Neuropsychiatric complications of...
  6. SNT Gatchaman

    Review Type I interferons and endoplasmic reticulum stress in health and disease, 2020, Sprooten and Garg

    Type I interferons and endoplasmic reticulum stress in health and disease Sprooten; Garg Type I interferons (IFNs) comprise of pro-inflammatory cytokines created, as well as sensed, by all nucleated cells with the main objective of blocking pathogens-driven infections. Owing to this broad range...
  7. SNT Gatchaman

    Type I Interferonopathy among Non-Elderly Female Patients with Post-Acute Sequelae of COVID-19, 2024, Xu, Qin

    Type I Interferonopathy among Non-Elderly Female Patients with Post-Acute Sequelae of COVID-19 Xu, Donghua; Qin, Xuebin The pathophysiological mechanisms of the post-acute sequelae of COVID-19 (PASC) remain unclear. Sex differences not only exist in the disease severity of acute SARS-CoV-2...
  8. SNT Gatchaman

    An aberrant immune–epithelial progenitor niche drives viral lung sequelae, 2024, Narasimhan et al.

    An aberrant immune–epithelial progenitor niche drives viral lung sequelae Narasimhan, Harish; Cheon, In Su; Qian, Wei; Hu, Sheng’en Shawn; Parimon, Tanyalak; Li, Chaofan; Goplen, Nick; Wu, Yue; Wei, Xiaoqin; Son, Young Min; Fink, Elizabeth; de Almeida Santos, Gislane; Tang, Jinyi; Yao, Changfu...
  9. SNT Gatchaman

    Immune system adaptation during gender-affirming testosterone treatment, 2024, Lakshmikanth, Brodin et al.

    Immune system adaptation during gender-affirming testosterone treatment Lakshmikanth, Tadepally; Consiglio, Camila; Sardh, Fabian; Forlin, Rikard; Wang, Jun; Tan, Ziyang; Barcenilla, Hugo; Rodriguez, Lucie; Sugrue, Jamie; Noori, Peri; Ivanchenko, Margarita; Piñero Páez, Laura; Gonzalez, Laura...
  10. SNT Gatchaman

    Cytokine Profile in Patients with Postacute Sequelae of COVID-19, 2024, Ghorra et al.

    Cytokine Profile in Patients with Postacute Sequelae of COVID-19 Nathalie Ghorra; Alexandros Popotas; Tatiana Besse-Hammer; Anne Rogiers; Francis Corazza; Carole Nagant The enduring impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its disease manifestation, COVID-19...
  11. SNT Gatchaman

    Interferon gene expression declines over time post-COVID infection and in long COVID patients, 2024, Gómez-Carballa et al.

    Interferon gene expression declines over time post-COVID infection and in long COVID patients A. Gómez-Carballa; S. Pischedda; J. Pardo-Seco; J. Gómez-Rial; F. Martinón-Torres; A. Salas BACKGROUND Interferons (IFNs) represent a first-line defense against viruses and other pathogens. It has been...
  12. SNT Gatchaman

    Review The Complex World of Kynurenic Acid: Reflections on Biological Issues and Therapeutic Strategy, 2024, Trevor Stone et al.

    The Complex World of Kynurenic Acid: Reflections on Biological Issues and Therapeutic Strategy Stone, Trevor W.; Darlington, L. Gail; Badawy, Abdulla A.-B.; Williams, Richard O. It has been unequivocally established that kynurenic acid has a number of actions in a variety of cells and tissues...
  13. SNT Gatchaman

    Interferon subverts an AHR–JUN axis to promote CXCL13+ T cells in lupus, 2024, Law et al.

    Interferon subverts an AHR–JUN axis to promote CXCL13+ T cells in lupus Law, Calvin; Wacleche, Vanessa Sue; Cao, Ye; Pillai, Arundhati; Sowerby, John; Hancock, Brandon; Horisberger, Alice; Bracero, Sabrina; Skidanova, Viktoriya; Li, Zhihan; Adejoorin, Ifeoluwakiisi; Dillon, Eilish; Benque, Isaac...
  14. pooriepoor91

    Preprint BioMapAI: Artificial Intelligence Multi-Omics Framework Modeling of Myalgic Encephalomyelitis / Chronic Fatigue Syndrome, 2024, Xiong et al.

    https://www.biorxiv.org/content/10.1101/2024.06.24.600378v1 BioMapAI: Artificial Intelligence Multi-Omics Framework Modeling of Myalgic Encephalomyelitis / Chronic Fatigue Syndrome Ruoyun Xiong, Elizabeth Fleming, Ryan Caldwell, Suzanne D. Vernon, Lina Kozhaya, Courtney Gunter, Lucinda...
    • pooriepoor91
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    • artificial intelligence bile acid biomapai gamma-delta t cells interferon interferon gamma lipids mait cells multi-omics
    • Replies: 16
    • Forum: ME/CFS research
  15. SNT Gatchaman

    Sex differences and immune correlates of Long COVID development, persistence, and resolution, 2024, Hamlin et al.

    Sex differences and immune correlates of Long COVID development, persistence, and resolution Rebecca E Hamlin; Shaun M Pienkos; Leslie Chan; Mikayla A Stabile; Kassandra Pinedo; Mallika Rao; Philip Grant; Hector Bonilla; Marisa Holubar; Upinder Singh; Karen B Jacobson; Prasanna Jagannathan...
    • SNT Gatchaman
    • Thread
    • ets1 integrins interferon interferon-y monocytes nf-κb nk cells sex differences t cells tgf-beta
    • Replies: 7
    • Forum: Long Covid research
  16. SNT Gatchaman

    TLR2/4 are novel activating receptors for SARS-CoV-2 spike protein on NK cells, 2024, Landolina et al.

    TLR2/4 are novel activating receptors for SARS-CoV-2 spike protein on NK cells Landolina, Nadine; Ricci, Biancamaria; Veneziani, Irene; Alicata, Claudia; Mariotti, Francesca Romana; Pelosi, Andrea; Quatrini, Linda; Mortari, Eva Piano; Carsetti, Rita; Vacca, Paola; Tumino, Nicola; Azzarone...
  17. SNT Gatchaman

    Preprint Transfer of IgG from Long COVID patients induces symptomology in mice, 2024, Vidarsson+

    Transfer of IgG from Long COVID patients induces symptomology in mice Vidarsson, G., Bos, A., van Vugt, M., den Dunnen, J., Wiersinga, W. J., Wust, R., Amsterdam UMC COVID-19 biobank,, Versteeg, S., Silva Santos Ribeiro, P., Willemen, H., Geyer, C. E., Larsen, M. D., Prado, J., Charlton, B...
  18. pooriepoor91

    Clinical and CSF single-cell profiling of post-COVID-19 cognitive impairment 2024 Hu et al

    Highlights • Improvement from post-COVID-19 cognitive impairment (CI) is slow • Post-COVID-19 CI is molecularly distinct from Alzheimer’s disease • Post-COVID-19 CI is associated with CSF monocyte recruitment and gene alterations • Improvement from post-COVID-19 CI is linked to greater CSF...
    • pooriepoor91
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    • alzheimers brain fog covid-19 interferon long covid pasc pegylated interferon lambda
    • Replies: 12
    • Forum: Long Covid research
  19. SNT Gatchaman

    MDA5-autoimmunity and interstitial pneumonitis contemporaneous with the COVID-19 pandemic MIP-C, 2024, David et al.

    MDA5-autoimmunity and interstitial pneumonitis contemporaneous with the COVID-19 pandemic MIP-C Paula David; Saptarshi Sinha; Khizer Iqbal; Gabriele De Marco; Sahar Taheri; Ella McLaren; Sheetal Maisuria; Gururaj Arumugakani; Zoe Ash; Catrin Buckley; Lauren Coles; Chamila Hettiarachchi; Emma...
  20. SNT Gatchaman

    Review SARS-CoV-2 Mitochondrial Metabolic and Epigenomic Reprogramming in COVID-19, 2024, Guarnieri et al.

    SARS-CoV-2 Mitochondrial Metabolic and Epigenomic Reprogramming in COVID-19 Guarnieri; Haltom; Albrecht; Lie; Olali; Widjaja; Ranshing; Angelin; Murdock; Wallace To determine the effects of SARS-CoV-2 infection on cellular metabolism, we conducted an exhaustive survey of the cellular metabolic...
    • SNT Gatchaman
    • Thread
    • atf6 cgas-sting epigenetics fgf21 gdf15 glycolysis hif-1 histone innate immune system integrated stress response interferon metabolic reprogramming metabolism mitochondria oxidative phosphorylation pentose phospate pathway perk tlr-9 upr
    • Replies: 2
    • Forum: Long Covid research
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