ABSTRACT
The complement system is a vital anti-microbial defence mechanism against circulating pathogens. Excessive complement activation can have deleterious outcomes for the host and is consequently tightly modulated by a set of membrane-associated and fluid-phase regulators of complement...
HbA1c and leukocyte mtDNA levels as major factors associated with post-COVID-19 syndrome in type 2 diabetes patients
Anton Matviichuk, Viktoriia Yerokhovych, Yeva Ilkiv, Dmytro Krasnienkov, Veronika Korcheva, Oleksandr Gurbych, Anna Shcherbakova, Pavlina Botsun, Tetyana Falalyeyeva, Oksana...
[Myalgic encephalomyelitis : etiopathogenesis, diagnosis and treatment]
(Full article in French)
Robin Scherrer, Marian Galovic, Markus Gschwind, Octavia Sabin
Published 17 July 2024
Abstract
Myalgic encephalomyelitis (ME), also known as chronic fatigue syndrome (CFS), is a neurological...
Altered spike IgG Fc N-linked glycans are associated with hyperinflammatory state in adult COVID and Multisystem Inflammatory Syndrome in Children
Jacob D. Sherman; Vinit Karmali; Bhoj Kumar; Trevor W. Simon; Sarah Bechnak; Anusha Panjwani; Caroline R. Ciric; Dongli Wang; Chris Huerta; Brandi...
Endometriosis, Pain, and Related Psychological Disorders: Unveiling the Interplay among the Microbiome, Inflammation, and Oxidative Stress as a Common Thread
Cuffaro, Francesca; Russo, Edda; Amedei, Amedeo
Endometriosis (EM), a chronic condition in endometrial tissue outside the uterus, affects...
Abstract
Background
This study investigates the impact of fluctuating lipid levels on endothelial dysfunction.
Methods
Human aortic and umbilical vein endothelial cells were cultured under varying palmitic acid (PA) concentrations: 0, 50, and 100 μM, and in a variability group alternating...
Cellular and Molecular Effects of Microgravity on the Immune System: A Focus on Bioactive Lipids
Fava, Marina; De Dominicis, Noemi; Forte, Giulia; Bari, Monica; Leuti, Alessandro; Maccarrone, Mauro
Microgravity is one of the main stressors that astronauts are exposed to during space missions...
Pain and the biochemistry of fibromyalgia: patterns of peripheral cytokines and chemokines contribute to the differentiation between fibromyalgia and controls and are associated with pain, fat infiltration and content
Gerdle, Björn; Dahlqvist Leinhard, Olof; Lund, Eva; Lundberg, Peter; Forsgren...
Chloride Homeostasis Regulates cGAS-STING Signaling
Jared Morse; Danna Wang; Serena Mei; Danielle Whitham; Colby Hladun; Costel C. Darie; Herman O Sintim; Modi Wang; KaHo Leung
The cGAS-STING signaling pathway has emerged as a key mediator of inflammation. However, the roles of chloride...
Blood Markers Show Neural Consequences of LongCOVID-19
Tang, Norina; Kido, Tatsuo; Shi, Jian; McCafferty, Erin; Ford, Judith M.; Dal Bon, Kaitlyn; Pulliam, Lynn
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) persists throughout the world with over 65 million registered cases of...
Rethinking coagulation: from enzymatic cascade and cell-based reactions to a convergent model involving innate immune activation
Yong, Jun; Toh, Cheng-Hock
Advancements in the conceptual thinking of hemostasis and thrombosis have been catalyzed by major developments within health research over...
Defining trained immunity and its role in health and disease
Netea, Mihai G.; Domínguez-Andrés, Jorge; Barreiro, Luis B.; Chavakis, Triantafyllos; Divangahi, Maziar; Fuchs, Elaine; Joosten, Leo A. B.; van der Meer, Jos W. M.; Mhlanga, Musa M.; Mulder, Willem J. M.; Riksen, Niels P.; Schlitzer...
Persistent CD8+ T cell proliferation and activation in COVID-19 adult survivors with post-acute sequelae: a longitudinal, observational cohort study of persistent symptoms and T cell markers
LaVergne, Stephanie M.; Dutt, Taru S.; McFann, Kim; Webb, Tracy L.; Henao-Tamayo, Marcela; Ryan...
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