inflammation

Scent of COVID-19: Whole-Genome Sequencing Analysis Reveals the Role of ACE2, IFI44, and NDUFAF4 in Long-Lasting Olfactory Dysfunction Beatrice Spedicati, Alessandro Pecori, Maria Pina Concas, Aurora Santin, Romina Ruberto, Giuseppe Giovanni Nardone, Andrea D’Alessandro, Giancarlo Tirelli...

Myeloid-Specific JAK2 Contributes to Inflammation and Salt Sensitivity of Blood Pressure Mohammad Saleem; Luul A. Aden; Ashley L. Mutchler; Chitra Basu; Lale A. Ertuglu; Quanhu Sheng; Niki Penner; Anna R. Hemnes; Jennifer H. Park; Jeanne A. Ishimwe; Cheryl L. Laffer; Fernando Elijovich...

ABSTRACT Ethnopharmacological relevance Chronic fatigue syndrome (CFS), as a complex, multisystemic, and multisystemic disorder affecting multiple organs and systems, often accompanies by symptoms such as post-exercise discomfort, sleep disorders, cognitive difficulties, and orthostatic...

Abstract: Current research into mood disorders indicates that circulating immune mediators participating in the pathophysiology of chronic somatic disorders have potent influences on brain function. This paradigm has brought to the fore the use of anti-inflammatory therapies as adjunctive to...

Unraveling SARS-CoV-2 Host-Response Heterogeneity through Longitudinal Molecular Subtyping Hospitalized COVID-19 patients exhibit diverse immune responses during acute infection, which are associated with a wide range of clinical outcomes. However, understanding these immune heterogeneities...

Exploring the landscape of symptom-specific inflammatory cytokines in post-COVID syndrome patients Chafik Tilikete, Imen Zamali, Zeineb Meddeb, Ghassen Kharroubi, Soumaya Marzouki, Tarak Dhaouadi, Ahlem Ben Hmid, Samar Samoud, Yousr Galai, Selma Charfeddine, Leila Abid, Salem Abdessalem, Jihène...

ABSTRACT The complement system is a vital anti-microbial defence mechanism against circulating pathogens. Excessive complement activation can have deleterious outcomes for the host and is consequently tightly modulated by a set of membrane-associated and fluid-phase regulators of complement...

HbA1c and leukocyte mtDNA levels as major factors associated with post-COVID-19 syndrome in type 2 diabetes patients Anton Matviichuk, Viktoriia Yerokhovych, Yeva Ilkiv, Dmytro Krasnienkov, Veronika Korcheva, Oleksandr Gurbych, Anna Shcherbakova, Pavlina Botsun, Tetyana Falalyeyeva, Oksana...

Proteomic aging clock predicts mortality and risk of common age-related diseases in diverse populations Argentieri, M. Austin; Xiao, Sihao; Bennett, Derrick; Winchester, Laura; Nevado-Holgado, Alejo J.; Ghose, Upamanyu; Albukhari, Ashwag; Yao, Pang; Mazidi, Mohsen; Lv, Jun; Millwood, Iona; Fry...

Revealing the Hidden Impacts: Insights into Biological Aging and Long-Term Effects in Pauci- and Asymptomatic COVID-19 Healthcare Workers Campisi, Manuela; Cannella, Luana; Bordin, Anna; Moretto, Angelo; Scapellato, Maria Luisa; Mason, Paola; Liviero, Filippo; Pavanello, Sofia; on behalf of...

[Myalgic encephalomyelitis : etiopathogenesis, diagnosis and treatment] (Full article in French) Robin Scherrer, Marian Galovic, Markus Gschwind, Octavia Sabin Published 17 July 2024 Abstract Myalgic encephalomyelitis (ME), also known as chronic fatigue syndrome (CFS), is a neurological...

Altered spike IgG Fc N-linked glycans are associated with hyperinflammatory state in adult COVID and Multisystem Inflammatory Syndrome in Children Jacob D. Sherman; Vinit Karmali; Bhoj Kumar; Trevor W. Simon; Sarah Bechnak; Anusha Panjwani; Caroline R. Ciric; Dongli Wang; Chris Huerta; Brandi...

Endometriosis, Pain, and Related Psychological Disorders: Unveiling the Interplay among the Microbiome, Inflammation, and Oxidative Stress as a Common Thread Cuffaro, Francesca; Russo, Edda; Amedei, Amedeo Endometriosis (EM), a chronic condition in endometrial tissue outside the uterus, affects...

Link to article By David Cox

Abstract Background This study investigates the impact of fluctuating lipid levels on endothelial dysfunction. Methods Human aortic and umbilical vein endothelial cells were cultured under varying palmitic acid (PA) concentrations: 0, 50, and 100 μM, and in a variability group alternating...

Now published - see post #6 Preprint Persistent Activation of Chronic Inflammatory Pathways in Long Covid Malika Aid; Katherine McMahan; Nicole Hachmann; Jessica Miller; Erica Borducchi; David Hope; Marjorie Rowe; Eleanor Schonberg; Siline Thai; Ai-ris Collier; Janet Mullington; Dan Barouch...

Cellular and Molecular Effects of Microgravity on the Immune System: A Focus on Bioactive Lipids Fava, Marina; De Dominicis, Noemi; Forte, Giulia; Bari, Monica; Leuti, Alessandro; Maccarrone, Mauro Microgravity is one of the main stressors that astronauts are exposed to during space missions...

Pain and the biochemistry of fibromyalgia: patterns of peripheral cytokines and chemokines contribute to the differentiation between fibromyalgia and controls and are associated with pain, fat infiltration and content Gerdle, Björn; Dahlqvist Leinhard, Olof; Lund, Eva; Lundberg, Peter; Forsgren...

Chloride Homeostasis Regulates cGAS-STING Signaling Jared Morse; Danna Wang; Serena Mei; Danielle Whitham; Colby Hladun; Costel C. Darie; Herman O Sintim; Modi Wang; KaHo Leung The cGAS-STING signaling pathway has emerged as a key mediator of inflammation. However, the roles of chloride...

Pituitary–Adrenal Axis and Peripheral Immune Cell Profile in Long COVID Alijotas-Reig, Jaume; Anunciacion-Llunell, Ariadna; Esteve-Valverde, Enrique; Morales-Pérez, Stephanie; Rivero-Santana, Sergio; Trapé, Jaume; González-García, Laura; Ruiz, Domingo; Marques-Soares, Joana; Miro-Mur, Francesc...