immune dysfunction

  1. forestglip

    Review Unravelling the Connection Between Energy Metabolism and Immune Senescence/Exhaustion in Patients with [ME/CFS], 2025, Campenhout et al

    Unravelling the Connection Between Energy Metabolism and Immune Senescence/Exhaustion in Patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Jente Van Campenhout, Yanthe Buntinx, Huan-Yu Xiong, Arne Wyns, Andrea Polli, Jo Nijs, Joeri L. Aerts, Thessa Laeremans, Jolien Hendrix...
    • forestglip
    • Thread
    • immune dysfunction immune exhaustion immune senescence me/cfs metabolic dysregulation
    • Replies: 4
    • Forum: ME/CFS research
  2. SNT Gatchaman

    Relapsing-Remitting Immunotherapy Responsive Small-Fiber Neuropathy, 2024, Oaklander et al.

    Relapsing-Remitting Immunotherapy Responsive Small-Fiber Neuropathy Anne Louise Oaklander, Julia Allen, Nadja Dietliker, Einar P. Wilder-Smith OBJECTIVES To expand understanding of the pathogenesis, presentations, and treatment of initially idiopathic small fiber polyneuropathy (SFN). METHODS...
  3. SNT Gatchaman

    Single-cell profiling identifies distinct hormonal, immunologic, and inflammatory signatures of endometriosis-constituting cells, 2023, Shin et al.

    Single-cell profiling identifies distinct hormonal, immunologic, and inflammatory signatures of endometriosis-constituting cells Sun Shin; Youn-Jee Chung; Seong Won Moon; Eun Ji Choi; Mee-Ran Kim; Yeun-Jun Chung; Sug Hyung Lee Endometriosis consists of ectopic endometrial epithelial cells...
  4. SNT Gatchaman

    Epigenetic memory of coronavirus infection in innate immune cells and their progenitors, 2023, Cheong et al.

    Epigenetic memory of coronavirus infection in innate immune cells and their progenitors Jin-Gyu Cheong; Arjun Ravishankar; Siddhartha Sharma; Christopher N. Parkhurst; Simon A. Grassmann; Claire K. Wingert; Paoline Laurent; Sai Ma; Lucinda Paddock; Isabella C. Miranda; Emin Onur Karakaslar...
    • SNT Gatchaman
    • Thread
    • bone marrow covid-19 epigenetics haematopoietic stem cell progenitors hspc il-6 immune dysfunction innate immune system monocytes stem cells trained innate immunity
    • Replies: 6
    • Forum: Long Covid research
  5. SNT Gatchaman

    Hypothesis Attenuation of ferroptosis as a potential therapeutic target for neuropsychiatric manifestations of post-COVID syndrome, 2023, Sousa et al.

    Attenuation of ferroptosis as a potential therapeutic target for neuropsychiatric manifestations of post-COVID syndrome Sousa, Ricardo A. L.; Yehia, Asmaa; Abulseoud, Osama A. Coronavirus disease-19 (COVID-19), caused by severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2), is...
    • SNT Gatchaman
    • Thread
    • cognitive dysfunction covid ferritin ferroptosis gpx4 immune dysfunction inflammation iron lipids long covid myelin neuropsychiatric disorders
    • Replies: 0
    • Forum: Long Covid research
  6. John Mac

    Investigating antibody reactivity to the intestinal microbiome in severe myalgic encephalomyelitis/chronic fatigue syndrome 2023 Carding et al

    Full title: Investigating antibody reactivity to the intestinal microbiome in severe myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) Preprint Abstract Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a multisystemic disease of unknown aetiology that is characterised...
    • John Mac
    • Thread
    • antibody carding igg immune dysfunction intestinal microbiome microbiome severe me
    • Replies: 3
    • Forum: ME/CFS research
  7. SNT Gatchaman

    Transforming Growth Factor-β: An Agent of Change in the Tumor Microenvironment, 2021, Stuelten et al.

    Transforming Growth Factor-β: An Agent of Change in the Tumor Microenvironment Stuelten, Christina H.; Zhang, Ying E. Transforming Growth Factor-β (TGF-β) is a key regulator of embryonic development, adult tissue homeostasis, and lesion repair. In tumors, TGF-β is a potent inhibitor of early...
    • SNT Gatchaman
    • Thread
    • aerobic glycolysis cancer immune dysfunction immune function metabolic reprogramming metabolism mitochondria oxidative phosphorylation tgf-beta tgf-β transforming growth factor tsp-1 tsp1
    • Replies: 7
    • Forum: Other health news and research
  8. SNT Gatchaman

    [Preprint] Post-COVID syndrome associated with capillary alterations, macrophage infiltration & distinct transcriptomic signatures in skeletal muscles

    Post-COVID syndrome is associated with capillary alterations, macrophage infiltration and distinct transcriptomic signatures in skeletal muscles Tom Aschman, Emanuel Wyler, Oliver Baum, Andreas Hentschel, Franziska Legler, Corinna Preusse, Lil Meyer-Arndt, Ivana Buettnerova, Alexandra Foerster...
    • SNT Gatchaman
    • Thread
    • capillaries cd169 immune dysfunction long covid macrophages microcirculation muscle muscle biopsy muscle weakness t-cells
    • Replies: 10
    • Forum: Long Covid research
  9. Sly Saint

    Stress-Induced Transcriptomic Changes in Females with ME/CFS Reveal Disrupted Immune Signatures, 2023, van Booven et al.

    Abstract Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a chronic, complex multi-organ illness characterized by unexplained debilitating fatigue and post-exertional malaise (PEM), which is defined as a worsening of symptoms following even minor physical or mental exertion. Our...
    • Sly Saint
    • Thread
    • exercise test gene expression immune dysfunction me/cfs pbmc
    • Replies: 26
    • Forum: ME/CFS research
  10. L

    Neuroimmune disorders in COVID-19 - Arino et al - 2022

    Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the aetiologic agent of the coronavirus disease 2019 (COVID-19), is now rapidly disseminating throughout the world with 147,443,848 cases reported so far. Around 30–80% of cases (depending on COVID-19 severity) are reported...
    • livinglighter
    • Thread
    • cytokines encephalitis encephalopathy immune activation immune dysfunction immune dysregulation immune response long covid neuroimmune neuroimmune disorders peripheral neuropathy vegf
    • Replies: 4
    • Forum: Long Covid research
  11. cassava7

    Phenotypic characteristics of peripheral immune cells of ME/CFS via transmission electron microscopy: A pilot study, Jahanbani et al, 2022

    Fereshteh Jahanbani, Rajan D. Maynard, Justin Cyril Sing, Shaghayegh Jahanbani, John J. Perrino, Damek V. Spacek, Ronald W. Davis, Michael P. Snyder Received: January 17, 2022; Accepted: July 25, 2022; Published: August 9, 2022 — Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is...
    • cassava7
    • Thread
    • electron microscopy immune dysfunction lipid droplets lipid metabolism lipids mitochondria mitochondrial architecture omf open medicine foundation ron davis smpd1 sphingolipids t cells
    • Replies: 25
    • Forum: ME/CFS research
  12. SNT Gatchaman

    Recovering or Persisting: The Immunopathological Features of SARS-CoV-2 Infection in Children, 2022, Buonsenso et al

    Recovering or Persisting: The Immunopathological Features of SARS-CoV-2 Infection in Children Buonsenso D, Valentini P, De Rose C, Tredicine M, Pereyra Boza MdC, Camponeschi C, Morello R, Zampino G, Brooks AES, Rende M, Ria F, Sanguinetti M, Delogu G, Sali M, Di Sante G, on behalf of the...
    • SNT Gatchaman
    • Thread
    • children covid-19 immune dysfunction immunology innate immune system long covid t cells
    • Replies: 2
    • Forum: Long Covid research
  13. Andy

    Sustained VWF-ADAMTS13 axis imbalance and endotheliopathy in Long COVID syndrome is related to immune dysfunction, 2022, Fogarty et al

    Abstract Background Prolonged recovery is common after SARs-CoV-2 infection, however the pathophysiological mechanisms underpinning Long COVID syndrome remain unknown. VWF-ADAMTS13 imbalance, dysregulated angiogenesis and immuno-thrombosis are hallmarks of acute COVID-19. We hypothesized that...
    • Andy
    • Thread
    • adamts13 endothelial immune dysfunction pf4 platelets vwf
    • Replies: 2
    • Forum: Long Covid research
  14. SNT Gatchaman

    Persistent Overactive Cytotoxic Immune Response in a Spanish Cohort of Individuals With Long-COVID: Identification of Diagnostic Biomarkers, 2022

    Persistent Overactive Cytotoxic Immune Response in a Spanish Cohort of Individuals With Long-COVID: Identification of Diagnostic Biomarkers Miguel Galan, Lorena Vigon, Daniel Fuertes, Marıa Aranzazu Murciano-Anton, Guiomar Casado-Fernandez, Susana Domınguez-Mateos, Elena Mateos, Fernando...
  15. MSEsperanza

    Evaluation of Immune Dysregulation in an Austrian Patient Cohort Suffering from Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, 2021, Lutz et al

    Lutz L, Rohrhofer J, Zehetmayer S, Stingl M, Untersmayr E. Evaluation of Immune Dysregulation in an Austrian Patient Cohort Suffering from Myalgic Encephalomyelitis/Chronic Fatigue Syndrome. Biomolecules. 2021; 11(9):1359. https://doi.org/10.3390/biom11091359 free full text...
    • MSEsperanza
    • Thread
    • 2021 austria immune activation immune deficiency immune dysfunction immune dysregulation lutz mannose-binding lectin mbl me/cfs paper
    • Replies: 10
    • Forum: ME/CFS research
  16. leokitten

    Gut microbiota composition reflects disease severity and dysfunctional immune responses in patients with COVID-19. Yeoh et al. Gut (2021)

    https://gut.bmj.com/content/early/2021/01/04/gutjnl-2020-323020
  17. Simon M

    The best evidence yet that immune system problems can cause ME/CFS? Simon M blog

    The best evidence yet that immune system problems can cause ME/CFS? Human leucocytes Antigen (HLA) proteins play an essential role in helping the immune system to recognise pathogens. This new research is easily the best study yet of HLA alleles (gene variants) in ME/CFS. It finds links...
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