hypoxanthine

  1. Sly Saint

    A map of metabolic phenotypes in patients with myalgic encephalomyelitis/chronic fatigue syndrome, 2021, Fluge, Mella et al

    Abstract Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating disease usually presenting after infection. Emerging evidence supports that energy metabolism is affected in ME/CFS, but a unifying metabolic phenotype has not been firmly established. We performed global...
  2. mango

    Open Sweden: ME/CFS lactate, glucose and hypoxanthine

    An ad is currently being circulated in Swedish ME groups on social media, a research study led by prof Jonas Bergquist at Uppsala University that is currently recruiting. It's a study on altered energy metabolism in ME/CFS, focusing mainly on lactate, glucose and hypoxanthine. (I couldn't find...
  3. Andy

    Hypoxanthine Induces Muscular ATP Depletion and Fatigue via UCP2, 2021, Yin et al

    Hypoxanthine (Hx), an intermediate metabolite of the purine metabolism pathway which is dramatically increased in blood and skeletal muscle during muscle contraction and metabolism, is characterized as a marker of exercise exhaustion. However, the physiological effects of Hx on skeletal muscle...
  4. Andy

    Post-Exertional Malaise Is Associated with Hypermetabolism, Hypoacetylation and Purine Metabolism Deregulation in ME/CFS Cases, 2019, McGregor et al

    Open access at https://www.mdpi.com/2075-4418/9/3/70
  5. adreno

    Metabolic profiling reveals anomalous energy metabolism and oxidative stress pathways in CFS, 2017, Armstrong et al

    Not new, but interesting and important: https://link.springer.com/article/10.1007/s11306-015-0816-5
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