gastrointestinal

Highlights Genetics of gut motility via data on stool frequency in 167,875 individuals GWAS identifies 14 loci associated with stool frequency Candidate genes enriched in neurotransmitter signaling and enteric motor neurons Polygenic scores predict increased risk of irritable bowel syndrome...

Abstract Functional Gastrointestinal Disorders (FGID) are Disorders of Gut-Brain Interaction (DGBI) recognized by a variety of symptoms caused by abnormalities within gastrointestinal (GI) motility, visceral hypersensitivity, altered mucosal and immune function, altered gut microbiota, and...

This survey study, nested within a prospective cohort of COVID-19 survivors with a minimum of 6 months of follow-up time, assessed the hypothesis that mental health symptoms both preceding and following COVID-19 infection would be associated with post-COVID chronic GI symptoms (see Methods...

Abstract Interferon-lambda (IFN-λ) is a recently described cytokine found to be of critical importance in innate immune regulation of intestinal viruses. Endogenous IFN-λ has potent antiviral effects and has been shown to control multiple intestinal viruses and may represent a factor that...

My daughter is 15, she has had ME/CFS now for 6 years. Gastro problems have always been a big part of her symptoms (stomach pain, lack of appetite, nausea, diarrhoea/cramps IBS type). She's got swallowing problems (waiting for a Paediatric SALT appointment) and she will have a Calprotectin...

Full title: Prevalence of gastrointestinal, cardiovascular, autonomic, and allergic manifestations in hospitalized patients with Ehlers-Danlos syndrome: a case-control study https://academic.oup.com/rheumatology/advance-article/doi/10.1093/rheumatology/keaa926/6067343

Full title: Functional gastrointestinal disorders are increased in joint hypermobility‐related disorders with concomitant postural orthostatic tachycardia syndrome Open access, https://onlinelibrary.wiley.com/doi/full/10.1111/nmo.13975?af=R

Hello Has anyone ever engaged in microbiome testing to explore comorbidities / alternative causes for CFS symptoms? I'm interested generally, but esp if UK based. Thanks all :)

SIBO (Small Intestine Bacterial Overgrowth) seems to be popping up on a few threads recently so I thought I’d start a poll about the prevalence among S4ME users. I suspect that it’s likely going to be a fairly low amount of people who answer yes to this, particularly as in the UK it’s...

Source: Zeitschrift fur Gastroenterologie Vol 56, #6, pp 573-577 Date: June 2018 URL: https://www.thieme-connect.de/products/ejournals/abstract/10.1055/a-0596-7981 Severe eosinophilic colitis caused by neuropathic agents in a patient with chronic fatigue syndrome and functional abdominal...

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