fibromyalgia

Full title: A paradigm for chronic fatigue syndrome: caught between idiopathic intracranial hypertension and spontaneous intracranial hypotension; caused by cranial venous outflow obstruction ABSTRACT Background Clinical similarities between chronic fatigue syndrome and idiopathic intracranial...

Abstract Objective: The identification of a complementary test to confirm the diagnosis of FM. The diagnosis of fibromyalgia (FM) is based on clinical features, but there is still no consensus, so patients and clinicians might benefit from such a test. Recent findings showed that pain lies in...

Abstract Objectives Over 1/3 of patients with rheumatoid arthritis (RA) exhibit evidence of fibromyalgianess, which is associated with higher rates of disability and inadequate responsiveness to RA treatment. Patients with RA often remain on glucocorticoids long-term, despite the known risk of...

Apologises if this has been posted - I searched and could not find it. Intramuscular Pressure is Almost Three Times Higher in Fibromyalgia Patients: A Possible Mechanism for Understanding the Muscle Pain and Tenderness https://www.jrheum.org/content/early/2020/09/10/jrheum.191068 Robert S...

Abstract Background Fibromyalgia (FM) is characterized by musculoskeletal pain, fatigue, sleep and memory disturbance. There is no definitive cure yet for FM-related health problems. Peroxisome proliferator-activated receptor’s (PPAR’s) activation is associated with insulin sensitisation and...

Abstract Introduction: Non-pharmacological approaches are recommended as first-line treatment for patients with fibromyalgia. This randomised controlled trial investigated the effects of a multicomponent rehabilitation programme for patients with recently diagnosed fibromyalgia in primary and...

Abstract Fibromyalgia syndrome (FMS) is characterized by widespread pain and tenderness, and patients typically experience fatigue and emotional distress. The etiology and pathophysiology of fibromyalgia are not fully explained and there are no effective drug treatments. Here we show that IgG...

[My bolding] Abstract Fibromyalgia presents with symptoms of widespread pain, fatigue, sleeping and cognitive disturbances as well as other somatic symptoms. It often overlaps with other conditions termed ‘central sensitivity syndromes’ such as irritable bowel syndrome, chronic fatigue...

Identification of differential genetic profiles in severe forms of fibromyalgia and chronic fatigue syndrome/myalgic encephalomyelitis: A population-based genetic association study Ferran J. Garcia-Fructuoso, Jose Ignacio Lao-Villadoniga, Cristina Santos, Violant Poca-Dias, Joaquim...

https://www.pharmiweb.com/press-release/2021-05-07/virios-therapeutics-to-present-at-the-benzinga-global-small-cap-conference

Abstract Background and Objectives Chronic widespread musculoskeletal pain (CWP) is a symptom of fibromyalgia and a complex trait with poorly understood pathogenesis. CWP is heritable (48-54%), but its genetic architecture is unknown and candidate gene studies have produced inconsistent results...

Ashok Gupta is citing this study as 'proof' that his programme is a cure for ME/CFS. Given that he is now actively targeting Covid LongHaulers, I thought it best to bring this to the attention of S4ME's resident experts. According to the comments on this youtube video, there are allegedly "3...

Abstract Background and Objectives: The aetiology and pathomechanism of fibromyalgia syndrome 12 (FMS) as one of chronic pain syndromes still need to be further elucidated. Mitogen-activated protein kinase (MAPK) pathway has been proposed as a novel approach in pain management. Since the major...

Abstract Background Fibromyalgia (FM) is a contested, chronic widespread pain syndrome on which recommended therapies have short-lasting, moderate effects. Nevertheless, some patients become symptom-free, and their recovery experiences inspired us to develop a patient-centred recovery-oriented...

Objective To identify correlates of quality of life (QoL) measured with the Quality of Life Scale (QOLS) in participants of a multidisciplinary day hospital treatment program for fibromyalgia (FM). Results The following variables could be identified as main correlates for QoL in FM, explaining...

Fibromyalgia is a syndrome that is characterized by widespread pain; fatigue; stiffness; reduced physical fitness; sleep disturbances; psychological symptoms, such as anxiety and depression; and deficits in cognitive functions, such as attention, executive function, and verbal memory deficits...

Most of this looks quite good, although it covers some psychological stuff including 'mindfulness' later: Fibromyalgia and pain: 'How cooking gave me my family back' - BBC News When you flick through a recipe book there are often brightly coloured photos of food, with texture and zing bursting...

Central sensitisation in chronic pain conditions: latest discoveries and their potential for precision medicine Authors include Nijs and Clauw. Published in the Lancet. Full paper here. Includes ‘chronic fatigue syndrome in the text and tables. Summary Chronic pain is a leading cause of...

Full title: Association of core body temperature and peripheral blood flow of the hands with pain intensity, pressure pain hypersensitivity, central sensitization, and fibromyalgia symptoms Our aim was to analyse body core temperature and peripheral vascular microcirculation at skin hypothenar...

Abstract Background: The aim of this registry study was the prospective evaluation of the efficacy of Pycnogenol® in idiopathic fibromyalgia (FM), over 4 weeks in comparison with the standard management (SM). Methods: A SM and a Pycnogenol®+SM group were formed. Pycnogenol® supplementation...