The Silent Virus Behind Mono Is Now a Prime Suspect in Major Diseases
Epstein-Barr virus, which causes glandular fever, was once dismissed as a rite of passage. Scientists now link it to cancer and multiple sclerosis.
Scientists are also reassessing the effects of other herpesviruses. Recent...
Cytomegalovirus seropositivity is associated with reduced risk of multiple sclerosis—a presymptomatic case–control study
Viktor Grut, Martin Biström, Jonatan Salzer, Pernilla Stridh, Daniel Jons, Rasmus Gustafsson, Anna Fogdell-Hahn, Jesse Huang, Nicole Brenner, Julia Butt, Noemi Bender, Anna...
Molecular Mimicry Between Epstein-Barr Virus and Human Herpesvirus-6 Proteins and Central Nervous System Proteins: Implications for T and B Cell Immunogenicity in an In Silico Study.
preprint
Abstract
Background: The Epstein-Barr virus (EBV) and human herpesvirus 6 (HHV-6) are frequently...
Full title:
Predisposing and Precipitating Factors in Epstein–Barr Virus-Caused Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
https://www.mdpi.com/2076-2607/13/4/702
Abstract
Long COVID following SARS-CoV-2 and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) following...
Abstract
In a subset of children and adolescents, SARS-CoV-2 infection induces a severe acute hyperinflammatory shock1 termed multisystem inflammatory syndrome in children (MIS-C) at four to eight weeks after infection. MIS-C is characterized by a specific T cell expansion2 and systemic...
Abstract
Post-acute sequelae of COVID-19 (PASC) is a complex and multifaceted clinical challenge requiring to emphasize its underlying pathophysiological mechanisms.
This study assessed hundreds of virological, serological, immunological, and tissue damage biomarkers in two patient cohorts who...
Highlights
Epstein-Barr virus (EBV) is the first identified oncogenic virus.
Globally, 1.5 % of human malignancies are attributed to EBV
EBV is associated with lymphomas, carcinomas, and auto-immune diseases.
Epstein-Barr Nuclear Antigen 1 (EBNA-1) is a key player in EBV-induced diseases...
Abstract
COVID-19 vaccines have prevented millions of COVID-19 deaths. Yet, a small fraction of the population reports a chronic debilitating condition after COVID-19 vaccination, often referred to as post- vaccination syndrome (PVS). To explore potential pathobiological features associated with...
Now published - link here
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Preprint
Full title: Reactivated EBV, HHV6, HAdV in Sputum from Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Patients: Are autoAbs to IFN-I Impairing Antiviral Immunity?
https://www.preprints.org/manuscript/202502.0185/v1
Abstract
An exhausted...
Abstract:
Background: Epstein-Barr virus (EBV) infection is a known trigger and risk factor for myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and post-COVID syndrome (PCS). In previous studies, we found enhanced IgG reactivity to EBV EBNA4 and EBNA6 arginine-rich sequences in...
Abstract
Background and Objectives
There is a strong link between Epstein-Barr virus (EBV) and multiple sclerosis (MS), but the underlying mechanisms are unclear. Patients with MS typically have a polyspecific intrathecal production of immunoglobulin G (IgG), part of which is directed against...
Antibody responses to Epstein-Barr virus, human herpesvirus 6 and human herpesvirus 7 in patients with chronic fatigue syndrome
T Sairenji, K Yamanishi, Y Tachibana, G Bertoni, T Kurata
Abstract
To test for an association between chronic fatigue syndrome (CFS) and infections with Epstein-Barr...
Detection of herpes viruses in patients with myalgic encephalomyelitis /chronic fatigue syndrome in Belarus
Svetlana Orlova, Galina Rudjko, Olga Orlova, Tatsiana Dakukina
Abstract
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a multifactorial chronic disease. The etiology and...
Lights and Shadows of Long COVID: Are Latent Infections the Real Hidden Enemy?
Francesca Serapide, Marisa Talarico, Salvatore Rotundo, Vittorio Pascale, Riccardo Serraino, Enrico Maria Trecarichi, Alessandro Russo
Abstract
Long COVID-19 (LC) is a poorly understood, multifactorial condition...
In summary, we report that MS patients are hallmarked by an accumulation of immune responses specifically directed against EBV EBNA381–452 and cross-reacting with CNS GlialCAM370–389–, CRYAB2–21–, MBP205–224–, and ANO2135–154–derived epitopes. Although, our findings provide additional insights...
Effect of high dose vitamin C on Epstein-Barr viral infection
Nina A Mikirova, Ronald Hunninghake
Background
Many natural compounds were tested for the ability to suppress viral replication. The present manuscript details an analysis of high dose vitamin C therapy on patients with EBV...
Exploring common pathogenic association between Epstein Barr virus infection and long-COVID by integrating RNA-Seq and molecular dynamics simulations
Kanwal, Ayesha; Zhang, Zhiyong
The term "Long-COVID" (LC) is characterized by the aftereffects of COVID-19 infection. Various studies have...
High Somatization Rates, Frequent Spontaneous Recovery, and a Lack of Organic Biomarkers in Post-Covid-19 Condition
Anna Tröscher; Patrick Gebetsroither; Marc Rindler; Vincent Böhm; Rainer Dormann; Tim von Oertzen; Anna Heidbreder; Raimund Helbok; Judith Wagner
INTRODUCTION
Many patients report...
Now published - see here
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An HERV-W ENV transcription in atypical memory B cells linked to COVID-19 evolution and risk for long COVID can express the encoded protein from a ribosome readthrough of mRNA from chromosome X.
Joanna Brunel; Julien Paganini; Melissa Galloux; Benjamin Charvet...
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