Abstract
Objective
Hypophosphatasia (HPP) is a rare disease characterized by incomplete or defective bone mineralization due to a mutation in the alkaline phosphatase (ALP) gene causing low levels of ALP. Disease presentation is heterogeneous and can present as a chronic pain syndrome like...
Composite reference standards are used to evaluate the accuracy of a new test in the absence of a perfect reference test. A composite reference standard defines a fixed, transparent rule to classify subjects into disease positive and disease negative groups based on existing imperfect tests. The...
Abstract
Background
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a multifaceted condition that affects most body systems. There is currently no known diagnostic biomarker; instead, diagnosis is dependent on application of symptom-based case criteria following exclusion of any...
I have a 23 and Me kit in my room for years. Hesitant to use it cause of privacy issues.
Was wondering are there tests that a doctor's office can run that would be similar to 23 and Me? Then I wouldn't have to be concerned about my results, how they are going to use it now or in the future...
One of the difficulties in studying and treating long COVID is that we don’t currently have a definitive way to diagnose it. And without a diagnostic test, the condition becomes much harder to manage or study. Eva Higginbotham spoke to Danny Altmann, an immunologist from Imperial College London...
Hi everyone,
I’m keen to know if any forum members have knowledge – or personal experience – of the role of peripheral nervous system tests in ME/CFS diagnosis and in symptom-specific treatments (examples: electromyography and nerve conduction studies; skin biopsy to evaluate epidermal nerve...
This US lab service claims to have great success diagnosing long covid patients and successfully treating them. They offer a lab assay of interleukins and cytokines. It’s not clear which are offered. The literature is not yet published.
https://covidlonghaulers.com/
interview with the founder...
full article here
https://www.labmedica.com/lab-technology/articles/294780480/fast-and-inexpensive-device-captures-and-identifies-viruses.html
research paper:
A rapid and label-free platform for virus capture and identification from clinical samples...
And the title is all I can access at the moment.
Paywalled at https://www.tandfonline.com/doi/full/10.1080/14737159.2020.1681976
Not currently available through Scihub.
Links to the thesis and other papers are in a post further down the thread
Merged thread
Andrew Pellegrini replicates Byron Hyde's findings (apparently)
"Apparently", because I haven't got the energy to read the article properly rather than just skimming.
Nanoelectric device could lead to a diagnostic blood test for ME/CFS
Last week, Dr Ron Davis’s team published a pilot study showing remarkable results for their nanoneedle device. Strikingly, there was no overlap between the results for 20 ME/CFS patients and those for 20 healthy controls...
By Open Medicine Foundation
full article here:
https://www.sanluisobispo.com/news/state/california/article229756099.html
[have looked at the link but can't find the published paper?]
eta: link now works
this one takes you to where it's listed...
Found this to be an interesting story. A Scottish women named Joy Milne says she can smell Parkinson's.
She is a former nurse and her husband developed the illness. Milne says she noticed the smell of Parkinson's ten years before her husband was diagnosed with the illness. After going to a...
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