diagnostic test

  1. Andy

    Could Some Patients With Fibromyalgia Potentially Have Hypophosphatasia? A Retrospective Single-Center Study 2023 Injean et al

    Abstract Objective Hypophosphatasia (HPP) is a rare disease characterized by incomplete or defective bone mineralization due to a mutation in the alkaline phosphatase (ALP) gene causing low levels of ALP. Disease presentation is heterogeneous and can present as a chronic pain syndrome like...
  2. cassava7

    Concerns about composite reference standards in diagnostic research, Dendukuri et al, 2018

    Composite reference standards are used to evaluate the accuracy of a new test in the absence of a perfect reference test. A composite reference standard defines a fixed, transparent rule to classify subjects into disease positive and disease negative groups based on existing imperfect tests. The...
  3. Wyva

    Review Biomarkers for myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS): a systematic review, 2023, Maksoud et al

    Abstract Background Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a multifaceted condition that affects most body systems. There is currently no known diagnostic biomarker; instead, diagnosis is dependent on application of symptom-based case criteria following exclusion of any...
  4. Y

    Options for genetic testing

    I have a 23 and Me kit in my room for years. Hesitant to use it cause of privacy issues. Was wondering are there tests that a doctor's office can run that would be similar to 23 and Me? Then I wouldn't have to be concerned about my results, how they are going to use it now or in the future...
  5. S

    Long COVID: Developing a diagnostic test

    One of the difficulties in studying and treating long COVID is that we don’t currently have a definitive way to diagnose it. And without a diagnostic test, the condition becomes much harder to manage or study. Eva Higginbotham spoke to Danny Altmann, an immunologist from Imperial College London...
  6. J

    Availability and usefulness of peripheral nervous system tests

    Hi everyone, I’m keen to know if any forum members have knowledge – or personal experience – of the role of peripheral nervous system tests in ME/CFS diagnosis and in symptom-specific treatments (examples: electromyography and nerve conduction studies; skin biopsy to evaluate epidermal nerve...
  7. B

    USA: InCellDx Dr Patterson - New lab service offering cytokine tests to Covid longhaulers

    This US lab service claims to have great success diagnosing long covid patients and successfully treating them. They offer a lab assay of interleukins and cytokines. It’s not clear which are offered. The literature is not yet published. https://covidlonghaulers.com/ interview with the founder...
  8. Dolphin

    Positive Tests for Lyme Disease and Emergency Department Visits for Bell's Palsy Patients, 2020, Pacheco et al.

    https://www.jem-journal.com/article/S0736-4679(20)30725-3/abstract
  9. J

    Permissive microbiome characterizes human subjects with a neurovascular disease cavernous angioma

    https://www.nature.com/articles/s41467-020-16436-w
  10. Sly Saint

    Cardiopulmonary Testing in ME/CFS to Improve Diagnostic Accuracy: due to be published Dec 2020

    University of Oslo https://www.clinicaltrials.gov/ct2/show/NCT02970240
  11. Sly Saint

    Article: Endometriosis ROSE Study Hopes to Create Diagnostic Tool Using Menstrual Blood

    full article here: https://themighty.com/2020/01/rose-study-endometriosis-diagnostic-test/
  12. Sly Saint

    Article: Fast and Inexpensive Device Captures and Identifies Viruses Jan 2020

    full article here https://www.labmedica.com/lab-technology/articles/294780480/fast-and-inexpensive-device-captures-and-identifies-viruses.html research paper: A rapid and label-free platform for virus capture and identification from clinical samples...
  13. Andy

    Editorial: Is a diagnostic blood test for chronic fatigue syndrome on the horizon?, 2019, Maes et al

    And the title is all I can access at the moment. Paywalled at https://www.tandfonline.com/doi/full/10.1080/14737159.2020.1681976 Not currently available through Scihub.
  14. Saz94

    Quantitative Electroencephalographic Assessment of ME/CFS. Support for a novel diagnostic protocol, 2019, Pellegrini. Student thesis.

    Links to the thesis and other papers are in a post further down the thread Merged thread Andrew Pellegrini replicates Byron Hyde's findings (apparently) "Apparently", because I haven't got the energy to read the article properly rather than just skimming.
  15. Simon M

    Nanoelectric device could lead to a diagnostic blood test for ME/CFS (Simon McGrath blog)

    Nanoelectric device could lead to a diagnostic blood test for ME/CFS Last week, Dr Ron Davis’s team published a pilot study showing remarkable results for their nanoneedle device. Strikingly, there was no overlap between the results for 20 ME/CFS patients and those for 20 healthy controls...
  16. Sly Saint

    A nanoelectronics-blood-based diagnostic biomarker for ME/CFS (2019) Esfandyarpour, Davis et al

    By Open Medicine Foundation full article here: https://www.sanluisobispo.com/news/state/california/article229756099.html [have looked at the link but can't find the published paper?] eta: link now works this one takes you to where it's listed...
  17. ME/CFS Skeptic

    Can one smell Parkinson's disease?

    Found this to be an interesting story. A Scottish women named Joy Milne says she can smell Parkinson's. She is a former nurse and her husband developed the illness. Milne says she noticed the smell of Parkinson's ten years before her husband was diagnosed with the illness. After going to a...
  18. John Mac

    Diagnostic sensitivity of 2-day cardiopulmonary exercise testing in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Nelson et al. 2019

    https://translational-medicine.biomedcentral.com/articles/10.1186/s12967-019-1836-0
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