biomarker

Identification of a multi-omics factor predictive of long COVID in the IMPACC study Gisela Gabernet; Jessica Maciuch; Jeremy P Gygi; John F Moore; Annmarie Hoch; Caitlin Syphurs; Tianyi Chu; Naresh Doni Jayavelu; David B Corry; Farrah Kheradmand; Lindsey R Baden; Rafick-Pierre Sekaly; Grace A...

Abstract Background Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a disease of unknown aetiology characterised by symptoms of post-exertional malaise (PEM) and fatigue leading to substantial impairment in functioning. Other key symptoms include cognitive impairment and...

Abstract Sleep deprivation enhances risk for serious injury and fatality on the roads and in workplaces. To facilitate future management of these risks through advanced detection, we developed and validated a metabolomic biomarker of sleep deprivation in healthy, young participants, across three...

full article Revolutionising Biomarker Discovery: The Role of High-Performance Liquid Chromatography

Proteomics International Laboratories Ltd (ASXIQ) Breakthrough Results For Endometriosis Diagnostic Blood Test

Katherine Huang, Alex G. C. de Sá, Natalie Thomas, Robert D. Phair, Paul R. Gooley, David B. Ascher & Christopher W. Armstrong Abstract Background Diagnosing complex illnesses like Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is complicated due to the diverse symptomology and...

Abstract The pathogenesis of Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) remains unclear, though increasing evidence suggests inflammatory processes play key roles. In this study, single-cell RNA sequencing (scRNA-seq) of peripheral blood mononuclear cells (PBMCs) was used to...

Plasma biomarkers in chronic single moderate–severe traumatic brain injury Gershon Spitz, Amelia J. Hicks, Stuart J. McDonald, Vincent Dore, Natasha Krishnadas, Terence J. O’Brien, William T O’Brien, Lucy Vivash, Meng Law, Jennie L. Ponsford, Christopher Rowe, Sandy R. Shultz Abstract Blood...

Impaired glymphatic function as a biomarker for subjective cognitive decline: An exploratory dual cohort study Yuxia Li, Luyao Wang, Jiayi Zhong, Huanyu Xu, Ying Han, Chuantao Zuo, Jiehui Jiang Background: Subjective cognitive decline (SCD) has been recognized as a potential risk stage for...

Abstract Background: Long coronavirus disease (COVID; LC) affects millions of people worldwide. The exact mechanisms which result in a broad, undulating and detrimental symptom profile remain unknown. Blood biomarkers associated with LC have been described; however, consensus on these remains...

Multikingdom and functional gut microbiota markers for autism spectrum disorder Published: 8 July 2024 Qi Su, Oscar W. H. Wong, Wenqi Lu, Yating Wan, Lin Zhang, Wenye Xu, Moses K. T. Li, Chengyu Liu, Chun Pan Cheung, Jessica Y. L. Ching, Pui Kuan Cheong, Ting Fan Leung, Sandra Chan, Patrick...

Skin Biopsy Detection of Phosphorylated α-Synuclein in Patients With Synucleinopathies Authors Abstract Importance Finding a reliable diagnostic biomarker for the disorders collectively known as synucleinopathies (Parkinson disease [PD], dementia with Lewy bodies [DLB], multiple system...

Thomas Vogl at the Medical University of Vienna, Austria, together with colleagues at the University Medical Center Groningen, the Netherlands, plan to use their Global Grant for Gut Health to identify potential biomarkers for long COVID by screening for antibodies against hundreds of thousands...

A Couple's Quest To Stop A Rare Disease Before It Takes One Of Them, 19 June 2017 (This is about fatal familial insomnia, a prion disease.) "In less than a year, Sonia's mom died. An autopsy showed Kamni had died from something rare -- a prion disease. Specifically, one called fatal familial...

Plasma proteomics identify biomarkers predicting Parkinson’s disease up to 7 years before symptom onset Jenny Hällqvist, Michael Bartl, Mohammed Dakna, Sebastian Schade, Paolo Garagnani, Maria-Giulia Bacalini, Chiara Pirazzini, Kailash Bhatia, Sebastian Schreglmann, Mary Xylaki, Sandrina Weber...

Salivary biomarkers as pioneering indicators for diagnosis and severity stratification of pediatric long COVID Sylwia D Tyrkalska, Fernando Pérez-Sanz, Lorena Franco-Martínez, Camila P Rubio, Asta Tvarijonaviciute, Silvia Martínez-Subiela, María Méndez-Hernández, Alba González-Aumatell, Clara...

I often hear the claim that the reason ME/CFS is neglected psychologised etc. is that we don’t have a biomarker for the disease. In my opinion, it is a possibility that we have a biomarker within the next decade, even though it might only be usable in specialist laboratories. How do you think...

Link to published version: https://www.s4me.info/threads/long-covid-plasma-levels-of-neurofilament-light-chain-in-mild-covid-19-patients-with-neurocognitive-symptoms-2023-gutman-et-al.33354/#post-529159 *** Preprint It is well known the potential of severe acute respiratory coronavirus type 2...

Identification of miR-30c-5p microRNA in Serum as a Candidate Biomarker to Diagnose Endometriosis Chico-Sordo, Lucía; Ruiz-Martínez, Tamara; Toribio, Mónica; González-Martín, Roberto; Spagnolo, Emanuela; Domínguez, Francisco; Hernández, Alicia; García-Velasco, Juan A. The diagnosis of...

Published as a preprint. See post #7 And now published in final form - link here ****** This is an abstract from the Demystifying Long COVID International Conference 2023, converted from an image on Twitter, so it might be slightly wonky, but it looks intriguing. Blood Transcriptomics Reveal...