Abstract:
We proposed that cerebrospinal fluid would provide objective evidence for disrupted brain metabolism in myalgic encephalomyelitis/chronic fatigue syndroome (ME/CFS). The concept of postexertional malaise (PEM) with disabling symptom exacerbation after limited exertion that does not...
Exertional Exhaustion Post-Exertional Malaise, PEM Evaluated by the Effects of Exercise on Cerebrospinal Fluid Metabolomics–Lipidomics and Serine Pathway in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
Baraniuk, James N.
Post-exertional malaise (PEM) is a defining condition of myalgic...
Reduced Natural Killer (NK) cell cytotoxicity is the most consistent immune finding in Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME/CFS). Meta-analysis of the published literature determined the effect size of the decrement in ME/CFS. Databases were screened for papers comparing NK...
Now published: link here
Preprint
Background. The Stroop task was used to investigate differences in cognitive function between Long COVID (LC), Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME/CFS) and healthy control subjects.
Methods. Subjects viewed four color words or neutral...
Abstract
Gulf War Illness (GWI) is a chronic condition characterized by multisystem symptoms that still affect up to one-third of veterans who engaged in combat in the Gulf War three decades ago. The aetiology of GWI is mainly explained by exposure to multiple toxic agents, vaccines, and...
Key Questions
What is myalgic encephalomyelitis or chronic fatigue syndrome (ME/CFS)?
Does ME/CFS involve more than just experiencing extreme fatigue?
How is ME/CFS diagnosed?
What is post-exertional malaise (PEM)?
What is the correlation between postural orthostatic tachycardia syndrome (POTS)...
Last reviewed: 10 Feb 2023, Last updated: 19 Jan 2022
Summary
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) can be distinguished from medical and psychiatric conditions in the differential diagnosis of fatigue by the presence of debilitating fatigue for more than 6 months...
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Review of the Midbrain Ascending Arousal Network Nuclei and Implications for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS), Gulf War Illness (GWI) and Postexertional Malaise (PEM)
Abstract
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS and Gulf War Illness (GWI) share...
Differential Effects of Exercise on fMRI of the Midbrain Ascending Arousal Network Nuclei in Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME/CFS) and Gulf War Illness (GWI) in a Model of Postexertional Malaise (PEM)
preprint
Abstract
Background: Myalgic Encephalomyelitis / Chronic...
Abstract
Aims
There is controversy about brain volumes in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (CFS) and Gulf War Illness (GWI). Subcortical regions were assessed because of significant differences in blood oxygenation level dependent signals in the midbrain between these...
Full title: Machine Learning Detects Pattern of Differences in Functional Magnetic Resonance Imaging (fMRI) Data between Chronic Fatigue Syndrome (CFS) and Gulf War Illness (GWI)
Open access, https://www.mdpi.com/2076-3425/10/7/456/htm
This is a follow-on from A Machine Learning Approach to...
Dr Baraniuk’s team. Full text here
Abstract
Gulf War Illness affects 25–32% of veterans from the 1990–91 Persian Gulf War.
Post-exertional malaise with cognitive dysfunction, pain and fatigue following physical and/or mental effort is a defining feature of Gulf War Illness.
We modelled...
Full Title:
A Machine Learning Approach to the Differentiation of Functional Magnetic Resonance Imaging Data of Chronic Fatigue Syndrome (CFS) From a Sedentary Control.
https://www.frontiersin.org/articles/10.3389/fncom.2020.00002/full
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