autophagy

  1. Sly Saint

    Elevated ATG13 in serum of pwME stimulates oxidative stress response in microglial cells , 2022, Gottschalk et al

    For the abstract of the published paper, go to post #9 Preprint Abstract Myalgic Encephalomyelitis and chronic fatigue syndrome is a multisystem illness characterized with extreme muscle fatigue associated with pain, neurocognitive impairment, and chronic inflammation. Despite intense...
  2. Andy

    SARS-CoV-2-mediated dysregulation of metabolism and autophagy uncovers host-targeting antivirals, 2021, Gassen et al

    Abstract Viruses manipulate cellular metabolism and macromolecule recycling processes like autophagy. Dysregulated metabolism might lead to excessive inflammatory and autoimmune responses as observed in severe and long COVID-19 patients. Here we show that SARS-CoV-2 modulates cellular...
  3. D

    Lipophagy confers a key metabolic advantage that ensures protective CD8A T-cell responses against HIV-1, 2020, Loucif et al

    https://www.tandfonline.com/doi/full/10.1080/15548627.2021.1874134 The news article got me interested because of the reference to "restores mitochondiral energy metabolism" Scientists demonstrated that the strength of elite controllers comes from their energy metabolism within CD8 lymphocytes...
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