autoimmune

The phenotypic and genetic association between endometriosis and immunological diseases Nina Shigesi, Holly R Harris, Hai Fang, Anne Ndungu, Matthew R Lincoln, The International Endometriosis Genome Consortium, The 23andMe Research Team, Chris Cotsapas, Julian Knight, Stacey A Missmer, Andrew P...

Autoimmune mechanisms elucidated through muscle acetylcholine receptor structures Huanhuan Li; Minh C. Pham; Jinfeng Teng; Kevin C. O’Connor; Colleen M. Noviello; Ryan E. Hibbs Skeletal muscle contraction is triggered by acetylcholine (ACh) binding to its ionotropic receptors (AChRs) at...

https://www.youcanknowthings.com/how-one-neuroscientist-solved-the-mystery-of-his-own-long-covid-2/ Interesting article, sadly few have access to this level of testing Ritixumab being used

Circulating Autoantibodies Against Vasoactive Biomarkers Related to Orthostatic Intolerance in Long COVID Patients Compared to No-Long-COVID Populations: A Case-Control Study Emilie Han, Katrin Müller-Zlabinger, Ena Hasimbegovic, Laura Poschenreithner, Nina Kastner, Babette Maleiner, Kevin...

Abstract Aberrant immune responses to viral pathogens contribute to pathogenesis, but our understanding of pathological immune responses caused by viruses within the human virome, especially at a population scale, remains limited. We analyzed whole-genome sequencing datasets of 6,321 Japanese...

Exploring the clinical and immunopathological association between Long COVID and Sjögren's Disease in mice and humans Sponsored by: Olink Proteomics +25pts SPEAKER Cuong Nguyen, PhD Associate Professor, University of Florida BIOGRAPHY EVENT DATE & TIME Date: May 30, 2024 Time: 9:00 AM...

Altered X-chromosome inactivation predisposes to autoimmunity CHRISTOPHE HURET, LÉA FERRAYÉ, ANTOINE DAVID, MYRIAME MOHAMED, NICOLAS VALENTIN, FRÉDÉRIC CHARLOTTE, MAGALI SAVIGNAC, MICHELE GOODHARDT, JEAN-CHARLES GUÉRY, CLAIRE ROUGEULLE, AND CÉLINE MOREY Abstract In mammals, males and females...

Hi all Ive just been reading about Rituximab within the context of autoimmune disease. Im aware of the CD20 and plasma (antibody generating) split within cells, but that for a lot of autoimmune diseases there is clinical response and patient symptom relief. We all know about the failed Ritux...

https://pubmed.ncbi.nlm.nih.gov/37147113/ Abstract Objective: Identify autoantibodies in anti-Ro/SS-A negative primary Sjögren's syndrome (SS). Methods: This is a proof-of-concept, case-control study of SS, healthy (HC) and other disease (OD) controls. A discovery dataset of plasma samples...

Metabolic Disorders Causing Fatigue in Sjogren’s Syndrome ABSTRACT NUMBER: 2546 Metabolic Disorders Causing Fatigue in Sjogren’s Syndrome Lakshmanan Suresh1, Julian Ambrus2, Long Shen3 and Sahana Vishwanath4, 160 Pineview Drive, State University of New York/Buffalo, Buffalo, NY, 2100 High St...

Please see below information about Dr Goebel’s inaugural lecture on the 27th of November 6pm – see details below this email. This can be accessed virtually and will be recorded to watch afterwards too. The lecture itself starts at 6pm. From ilcamsevents: ilcamsevents@liverpool.ac.uk Dear...

Hi all, its appears a German Dr, Dr Habets who is an Oncologist, is undertaking a trial (or just randomly treating its very hard to tell) with Rituximab in Long COVID and Me/cfs patients who test positive for GCPR aabs via bioassay (ie not ELISA). Its REALLY hard to fully understand what is...

Autoimmune and Autoinflammatory Connective Tissue Disorders Following COVID-19 Sung Ha Lim; Hyun Jeong Ju; Ju Hee Han; Ji Hae Lee; Won-Soo Lee; Jung Min Bae; Solam Lee Importance Multiple cases of autoimmune and autoinflammatory diseases after COVID-19 have been reported. However, their...

Psychiatric Symptoms in Acute and Persisting Forms of COVID-19 Associated with Neural Autoantibodies Hansen, Niels (1) Background: In this narrative review, we focus on neural autoantibodies in patients with coronavirus disease 2019 (COVID-19) as a consequence of severe acute respiratory...

Long COVID-19 Cardiac Complications Are Associated With Autoimmunity to Cardiac Self-Antigens Sufficient to Cause Cardiac Dysfunction No access to the paper... https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.122.062672 A post by Eric Topol .

Pediatric de novo movement disorders and ataxia in the context of SARS-CoV-2 Wilpert, Nina-Maria; de Almeida Marcelino, Ana Luísa; Knierim, Ellen; Incoronato, Pasquale; Sanchez-Sendin, Elisa; Staudacher, Olga; Drenckhahn, Anne; Bittigau, Petra; Kreye, Jakob; Prüss, Harald; Schuelke, Markus...

Are the integrin binding motifs within SARS CoV-2 spike protein and MHC class II alleles playing the key role in COVID-19? Gerencer, Marijan; McGuffin, Liam J. The previous studies on the RGD motif (aa403-405) within the SARS CoV-2 spike (S) protein receptor binding domain (RBD) suggest that...

Extensive Brain Pathologic Alterations Detected with 7.0-T MR Spectroscopic Imaging Associated with Disability in Multiple Sclerosis Eva Heckova; Assunta Dal-Bianco; Bernhard Strasser; Gilbert J. Hangel; Alexandra Lipka; Stanislav Motyka; Lukas Hingerl; Paulus S. Rommer; Thomas Berger; Petra...

High risk of autoimmune diseases after COVID-19 Chetan Sharma & Jagadeesh Bayry Nature Reviews Rheumatology (2023) - Full Text ABSTRACT: The full picture of post-COVID-19 autoimmune diseases and their prevalence is lacking despite numerous case reports and small series. Two studies that use...

I don't know if this has been posted elsewhere but I thought it was very interesting. I wonder if something like this might end up being helpful for a subset of pwME... https://www.theguardian.com/science/2022/sep/15/scientists-hail-autoimmune-disease-therapy-breakthrough-car-t-cell-lupus "In...