Serum antineuronal antibodies in patients with post-COVID-19 condition − association to intensive care
Tatiana Posharina, Mikko Varonen, Hanna Jarva, Mari Kanerva, Helena Liira, Sini M Laakso
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Highlights
• Antineuronal antibodies found in 12.1% of post-COVID-19 patients...
Postacute COVID-19 syndrome and fibromyalgia syndrome are associated with anti-satellite glial cell IgG serum autoantibodies but only fibromyalgia syndrome serum-IgG is pronociceptive
Berwick, Richard J.; Sahbaie, Peyman; Kenny, Grace; Guo, Tian-Zhi; Neiland, Harvey; Andersson, David A.; Clark...
Immunotherapies for Postural Orthostatic Tachycardia Syndrome, Other Common Autonomic Disorders and Long COVID: Current State and Future Direction
Blitshteyn, S., Funez-dePagnier, G., Szombathy, A., & Hutchinson, M
Abstract
Postural orthostatic tachycardia syndrome (POTS), neurocardiogenic...
Introduction:
Following the shift of SARS-CoV-2 from pandemic to endemic, post COVID syndrome (PCS) joins the list of already known post-acute infection syndromes (PAIS) and its most severe manifestation, myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). The exact pathomechanism of...
Abstract
COVID-19 vaccines have prevented millions of COVID-19 deaths. Yet, a small fraction of the population reports a chronic debilitating condition after COVID-19 vaccination, often referred to as post- vaccination syndrome (PVS). To explore potential pathobiological features associated with...
Highlights
•FM patients have higher anti-SGC IgG levels associated with pain intensity
•FM patients have lower levels of phospholipid classes, sphingomyelin, and triglycerides
•FM patients have higher levels of diglycerides
•FM severe have higher levels of some lysophosphatidylcholines than FM...
Abstract:
Post-COVID syndrome (PCS) has emerged as a significant health concern with persisting symptoms. A subset of PCS patients develops severe myalgic encephalomyelitis/chronic fatigue syndrome (pcME/CFS). Dysregulated autoantibodies (AABs) have been implicated in PCS, contributing to immune...
Association Between NK Cell Genetic Variants and the Development of Long COVID Associated- and Prepandemic Small Fiber Neuropathy
Marianne Graninger; Verena Endmayr; Laura M. Kühner; Sarah M. Berger; Paulus Rommer; Sigrid Klotz; Ellen Gelpi; Hannes Vietzen; Romana Höftberger; Elisabeth...
Autoantibodies, Polymorphisms in the Serotonin Pathway, and Human Leukocyte Antigen Class II Alleles in Chronic Fatigue Syndrome
Oscar-Danilo Ortega-Hernandez, Mariaclara Cuccia, Sara Bozzini, Nicola Bassi, Samuel Moscavitch, Lina-Marcela Diaz-Gallo, Miri Blank, Nancy Agmon-Levin, Yehuda...
Preprint
Link to published paper here
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The Lancet: Efficacy of Repeat Immunoadsorption in Post-COVID ME/CFS Patients with Elevated B2-Adrenergic Receptor Autoantibodies: A Prospective Cohort Study
Abstract
Background: Since the pandemic, SARS-CoV-2 has become the leading trigger for ME/CFS...
Objective: The long-lasting persistence of autoantibodies stands as one of the hypotheses explaining the multisystemic manifestations seen in individuals with post-COVID-19 condition. The current review offers restricted insights into the persistence of autoantibodies in plasma/serum in people...
A causal link between autoantibodies and neurological symptoms in long COVID
Abstract
Acute SARS-CoV-2 infection triggers the generation of diverse and functional autoantibodies (AABs), even after mild cases. Persistently elevated autoantibodies have been found in some individuals with long...
Now published - link here
Preprint
Prevalent and persistent new-onset autoantibodies in mild to severe COVID-19
Abstract
Autoantibodies have been shown to be implied in COVID-19 but the emerging autoantibody repertoire remains largely unexplored. We investigated the new-onset autoantibody...
https://pubmed.ncbi.nlm.nih.gov/37147113/
Abstract
Objective: Identify autoantibodies in anti-Ro/SS-A negative primary Sjögren's syndrome (SS).
Methods: This is a proof-of-concept, case-control study of SS, healthy (HC) and other disease (OD) controls. A discovery dataset of plasma samples...
Please see below information about Dr Goebel’s inaugural lecture on the 27th of November 6pm – see details below this email. This can be accessed virtually and will be recorded to watch afterwards too. The lecture itself starts at 6pm.
From ilcamsevents: ilcamsevents@liverpool.ac.uk
Dear...
Brain-targeted autoimmunity is strongly associated with Long COVID and its chronic fatigue syndrome as well as its affective symptoms.
Abstract
Background:
Autoimmune responses contribute to the pathophysiology of Long COVID, affective symptoms and myalgic encephalomyelitis/chronic fatigue...
Examination of autoantibodies to type I interferon in patients suffering from long COVID
Kristoffer Skaalum Hansen; Sofie Eg Jørgensen; Morten Kelder Skouboe; Jane Agergaard; Berit Schiøttz-Christensen; Line Khalidan Vibholm; Martin Tolstrup; Lars Østergaard; Steffen Leth; Trine H. Mogensen...
Severity of neurological long-COVID symptoms correlates with increased level of autoantibodies targeting vasoregulatory and autonomic nervous system receptors
Abstract
Background
The Long-COVID syndrome constitutes a plethora of persisting symptoms with neurological disorders being the most...
Full title: Anti-satellite glia cell IgG antibodies in fibromyalgia patients are related to symptom severity and to metabolite concentrations in thalamus and rostral anterior cingulate cortex
Highlights
FMS have higher anti-SGC IgG levels compared to healthy controls.
FMS with high, compared...
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