2022

  1. Andy

    Persistent Autoimmune Activation and Proinflammatory State in Post-COVID Syndrome, 2022, Acosta-Ampudia et al

    Abstract Background The immunopathological pathways enabling post-COVID syndrome (PCS) development are not entirely known. We underwent a longitudinal analysis of patients with COVID-19 who developed PCS aiming to evaluate the autoimmune and immunological status associated with this condition...
  2. Andy

    Chronic Fatigue and Postexertional Malaise in People Living with Long COVID: An Observational Study, 2022, Twomey et al

    Abstract Objectives People living with long COVID describe a high symptom burden, and a more detailed assessment is needed to inform rehabilitation recommendations. The objectives were to use validated questionnaires to measure the severity of fatigue and compare this with normative data and...
  3. Noir

    2022 Petition: Denmark must follow international evidence-based guidelines for ME (anyone can sign)

    The Danish Health Authorities rejects the new NICE guidelines and keep clinging to CBT and GET. Please sign and share this petition to help put pressure on the Danish Health Authorities so they will start following current biomedical science. I've linked both an English translation and the...
  4. Wyva

    “I feel like my body is broken”: Exploring the experiences of people living with long COVID, 2022, Wurz et al

    Abstract Background: Long COVID, an illness affecting a subset of individuals after COVID-19, is distressing and poorly understood. Exploring the experiences of people with long COVID could help inform current conceptualizations of the illness, guide supportive care strategies, and validate...
  5. Andy

    Generalised worry in patients with [CFS] following Cognitive Behavioural Therapy - a prospective cohort study in secondary care, 2022, Chalder et al

    Full title: Generalised worry in patients with Chronic Fatigue Syndrome following Cognitive Behavioural Therapy - a prospective cohort study in secondary care Highlights • Generalised worry is highly prevalent in Chronic Fatigue Syndrome (CFS). • Worry was linked with greater fatigue, anxiety...
  6. Sly Saint

    Review of the Midbrain Ascending Arousal Network Nuclei and Implications for (ME/CFS), Gulf War Illness (GWI) and (PEM), 2022, Baraniuk

    Review of the Midbrain Ascending Arousal Network Nuclei and Implications for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS), Gulf War Illness (GWI) and Postexertional Malaise (PEM) Abstract Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS and Gulf War Illness (GWI) share...
  7. Sly Saint

    Psychological Predictors of Self-reported COVID-19 Outcomes: Results From a Prospective Cohort Study, 2022, Ayling, Chalder et al

    Abstract Background Previous research has shown that psychological factors, such as stress and social support, are associated with greater susceptibility to viral respiratory illnesses and more severe symptoms. During the COVID-19 pandemic there has been a well-documented deterioration in...
  8. Wyva

    Assessment of Functional Mobility After COVID-19 in Adults Aged 50 Years or Older in the Canadian Longitudinal Study on Aging, 2021, Beauchamp et al

    Key Points Question What is the association of a COVID-19 diagnosis and mobility and physical function among community-living middle-aged and older Canadians during the initial pandemic lockdown in 2020? Findings This cohort study of 24 114 participants found that community-living...
  9. Hoopoe

    Longitudinal analysis reveals high prevalence of Epstein-Barr virus associated with multiple sclerosis, Bjornevik et al (2022)

    Main paper Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system of unknown etiology. We tested the hypothesis that MS is caused by Epstein-Barr virus (EBV) in a cohort comprising more than 10 million young adults on active duty in the US...
  10. Andy

    Mild respiratory COVID can cause multi-lineage neural cell and myelin dysregulation, 2021, Fernandez, Monje, Nath et al

    Mild respiratory SARS-CoV-2 infection can cause multi-lineage cellular dysregulation and myelin loss in the brain Preprint Abstract Survivors of Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) infection frequently experience lingering neurological symptoms, including impairment in...
  11. Sly Saint

    Commonalities in the Features of Cancer and Chronic Fatigue Syndrome (CFS): Evidence for Stress-Induced Phenotype Instability?, 2022, Rusin et al

    Abstract Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME) and Cancer-Related Fatigue (CRF) are syndromes with considerable overlap with respect to symptoms. There have been many studies that have compared the two conditions, and some of this research suggests that the etiologies of...
  12. Sly Saint

    Psychogenic Pseudosyncope: Real or Imaginary? Results from a Case-Control Study in (ME/CFS) Patients, 2022, Visser

    Abstract Background and objectives: Orthostatic intolerance (OI) is a clinical condition in which symptoms worsen upon assuming and maintaining upright posture and are ameliorated by recumbency. OI has a high prevalence in patients with myalgic encephalomyelitis/chronic fatigue syndrome...
  13. Sly Saint

    The complex syndrome of functional neurological disorder, 2022, Edwards et al

    Abstract Background Patients with functional neurological disorders (FND) often present with multiple motor, sensory, psychological and cognitive symptoms. In order to explore the relationship between these common symptoms, we performed a detailed clinical assessment of motor, non-motor...
  14. Sly Saint

    PaxMedica Plans to Initiate Phase 1B Study for PAX-101 (Suramin) in Patients with Long COVID-19 Syndrome

    Study has been approved by the South African Health Authority for individuals with documented COVID-19 infections who develop debilitating physical and neuropsychiatric symptoms that persist for more than 12 weeks after the viral infection has passed - Enrollment is expected to commence in Q1...
  15. Sly Saint

    Symptom-based Rehabilitation Compared to Usual Care in Post-COVID - a RCT (RELOAD) 2021/22 Germany

    Recruitment Status : Not yet recruiting Sponsor: Schön Klinik Berchtesgadener Land Collaborators: Bavarian State Office for Health and Food Safety Praxis im Zentrum Erlangen Pneumologen Lichterfelde Berlin Pneumopraxis Marburg COVID ambulance Philipps-University Marburg Pneumologie Elisenhof...
  16. Andy

    Sustained improvement with mindfulness-based therapy for psychogenic nonepileptic seizures, 2022, Baslet, Ridlon, Raynor, Gonsalvez and Dworetzky

    Highlights Follow-up after mindfulness-based therapy for PNES conducted at 3–6 months. Fourteen (54%) of 26 patients attended follow-up. PNES frequency, intensity, and days per week with PNES remained improved. Illness perception, worry, and feeling understood improved over the course of MBT...
  17. Andy

    The Netherlands - €28.5 million ME/CFS research program - ZonMW funding awards announced April 2023

    "DUTCH ZONMW RESEARCH PROGRAMME LAUNCHED One of the topics discussed in News from the Netherlands in this issue is the approval of a 10 year Biomedical Research Program with a subsidy of € 28,5 million. Just before releasing this issue, Dutch ZonMW – who executes the programme and compiled its...
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