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Abstract Post –acute sequalae of COVID-19 (PASC) among U.S. military members remains unexplored. A cohort study of U. S. military members who had a COVID-19 test result, with the specimen collected between March 1, 2020 and November 30, 2021 was conducted. Demographic, inpatient and outpatient...

Background: Fibrin(ogen) amyloid microclots and platelet hyperactivation are key pathological findings in patients with acute COVID-19 infection and also in those with Long COVID/Post-Acute Sequelae of COVID-19 (PASC). These pathologies may represent a suitable target for pharmacological...

Back on topic. Trial By Error: What the Hell is Going on with Cochrane’s Long-Delayed Re-Review of “Exercise Therapies”? "What is going on with Cochrane’s much-delayed re-review of exercise therapy for the illness the organization is these days calling ME/CFS? It is more than three years since...

Discussion thread here, Preprint: Developing a blood cell-based diagnostic test for ME/CFS using peripheral blood mononuclear cells 2023 Xu et al

Abstract As six patient partners in Canada, we aim to contribute to learning and to provide an opportunity to reflect on patient engagement (PE) in research and healthcare environments. Patient engagement refers to “meaningful and active collaboration in governance, priority setting, conducting...

While psychiatric manifestations are common in patients with Cushing’s syndrome (CS), to our knowledge, there are no reported cases of CS presenting with functional neurological disorder (FND), a neuropsychiatric condition in which patients experience neurological symptoms, such as motor...

Objective To determine the effect of covid-19 vaccination, given before and after acute infection with the SARS-CoV-2 virus, or after a diagnosis of long covid, on the rates and symptoms of long covid. Design Systematic review. Data sources PubMed, Embase, and Cochrane covid-19 trials, and...

Introduction: Similar to what it has been reported with preceding viral epidemics (such as MERS, SARS, or influenza), SARS-CoV-2 infection is also affecting the human immunometabolism with long-term consequences. Even with underreporting, an accumulated of almost 650 million people have been...

Background The scale of COVID-19 and its well documented long-term sequelae support a need to understand long-term outcomes including frailty. Methods This prospective cohort study recruited adults who had survived hospitalisation with clinically diagnosed COVID-19 across 35 sites in the UK...

BACKGROUND: Myalgic encephalomyelitis (ME) is a complex, multi-system neurological condition. The defining feature of ME is post-exertional malaise (PEM) with over 30 symptoms triggered by physical, cognitive, emotional and social activity. The cause of PEM is unclear but one area of research...

BACKGROUND: Existing instruments often are inappropriate to measure the effects of post-exertional malaise (PEM) and post-exertional symptom exacerbation (PESE) on activities of daily living (ADLs). A validated questionnaire to measure self-reported ability with ADLs would advance research and...

BACKGROUND: Post-exertional malaise (PEM) is the hallmark symptom of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) yet its diverse manifestations make it difficult to recognize. Brief instruments for detecting PEM are critical for clinical and scientific progress. OBJECTIVE: To...

Preprint. Paper now published, see this post Abstract A blood-based diagnostic test for myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and multiple sclerosis (MS) would be of great value in both conditions, facilitating more accurate and earlier diagnosis, helping with current...

An alternate suggestion that we have been using to help with noise from other flats is a white noise generator. Lots of options out there, and perhaps might not be suitable for your situation, but we have found that it definitely helps to make noise from elsewhere less disturbing to us.

More from the post that John Mac linked to

Published papers thread for w/c 13th March. Facebook: https://www.facebook.com/sci4me/posts/pfbid02mSFyuTg5gVhdykEj1nTTGRjodWmfyyeU7HYUYtsmcT9XQ7c3YVyvk1NsAVdXwSo7l Mastodon: https://med-mastodon.com/@s4me/110055051421628426

News in Brief posts for w/c 13th March. Facebook: https://www.facebook.com/sci4me/posts/pfbid0CuewzMtTgxAkPSqpBLtetkbYeQ3fpHVp2cU3i4sofrnmpXv4EhEWvfGXBxVu6zDMl Mastodon: https://med-mastodon.com/@s4me/110050102951042269

Highlights Limited treatment options exist for patients with functional neurological disorders. Psychotherapeutic treatments show encouraging results for FND in research settings. A limited number of published studies explore motor and seizure FND outcomes in the natural outpatient clinic...

Several major epidemiological studies have been funded in the UK with the goal of better understanding the epidemiology of persistent symptoms following SARS-CoV-2 infection. Investigators from nine of these studies formed the National Long COVID Research Working Group in 2021 to share key...

"4.2 Characterization of exhaustion disorder Demographic and clinical data collected from ED-participants through closed-ended questions and symptom questionnaires in the present study indicate a clinical picture that is similar to findings from previous qualitative and quantitative inquiries...