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Attendance Allowance is a non-means-tested weekly payment to help cover costs of pensioners (aged 66+) who need someone to 'attend' them. You can get it if you have a long-term health condition that means you need help with daily tasks. This includes sensory disabilities (such as blindness), or...

Last day to post your DNA sample kits, if you haven't done so already!

"We're pleased to announce a new resource – a downloadable one-sheet titled “How to work safely with people who have ME/CFS”. This is aimed at physios who do not work in specialist ME services, to help them understand how to adapt their practice to work safely with people who have ME. The new...

Trial By Error: Yet Another Meta-Analysis Purporting to Prove that CBT Is Effective for “Chronic Fatigue Syndrome” I just wrote about how PACE was favorably cited in an article in Nature Reviews Cardiology. Last month, that piece of crap was also included as part of yet another meta-analysis...

"With reported higher levels of online activity for people with ME/CFS than other patient groups (Westerby 2013 cited in Ytre-Arne) it is crucial to gain more knowledge of usage characteristics and experience of online use, and its integration into everyday life. This scoping review protocol...

CCC criteria for the ME/CFS cohort. Frustratingly, as far as I could see, they don't report if they recorded length of illness, even though they use (unspecified) length of illness as a possible explanation for the difference between PCC and ME/CFS cohorts.

‘Wildly weird’ RNA bits discovered infesting the microbes in our guts https://www.nature.com/articles/d41586-024-00266-7

Abstract Nutrition has broad impacts on all physiological processes. However, how nutrition affects human immunity remains largely unknown. Here we explored the impact of a dietary intervention on both immunity and the microbiota by performing a post hoc analysis of a clinical trial in which...

Full title: Psychometric evaluation of the DePaul Symptom Questionnaire-Short Form (DSQ-SF) among adults with Long COVID, ME/CFS, and healthy controls: A machine learning approach. Abstract Long COVID shares a number of clinical features with myalgic encephalomyelitis/chronic fatigue syndrome...

"I. INTRODUCTION Long COVID impacts the health and economic security of millions. Yet, because it is a recent phenomenon and remains difficult to diagnose, people unable to work due to Long COVID are experiencing additional barriers to accessing Social Security Disability Insurance (“SSDI”)...

Obesity drugs have another superpower: taming inflammation The latest generation of anti-obesity drugs has taken the world by storm, thanks to their effectiveness at treating diabetes and reducing weight. But these drugs also have a less well-known superpower: the ability to suppress...

Highlights GLP-1R agonism attenuates TLR-induced inflammation Semaglutide reduces the severity of polymicrobial inflammation Anti-inflammatory actions of GLP-1R agonists require CNS GLP-1Rs GLP-1R agonists reduce inflammation through CNS adrenergic and opioid GPCRs Summary Glucagon-like...

Twitter thread on this topic from @PeterW "A few people asking about this, so here’s some more info. The NHS website text was updated 18 months ago by two people well placed to do so who are, I believe, fully supported by the ME community, one of whom has ME. This was done as part of the DHSC...

Published papers thread for w/c 22nd Jan. Facebook: https://www.facebook.com/sci4me/posts/pfbid0MQG64LwuAtB2MZsNa8Ejfqp5H57QkngTDmxQej6yNa1rwYEvs7yJJ52HDxFtLNJWl Mastodon: https://med-mastodon.com/@s4me/111838790822400838

Posted on Twitter by the Cochrane Consumers account..... "The University of Alberta’s free online critical thinking and science literacy course to help people differentiate science from pseudoscience" https://www.ualberta.ca/admissions-programs/online-courses/science-literacy.html I wonder if...

‘It’s insane’: New viruslike entities found in human gut microbes As they collect and analyze massive amounts of genetic sequences from plants, animals, and microbes, biologists keep encountering surprises, including some that may challenge the very definition of life. The latest, reported this...

Link to post with published version Preprint Abstract Here, we describe the “Obelisks,” a previously unrecognised class of viroid-like elements that we first identified in human gut metatranscriptomic data. “Obelisks” share several properties: (i) apparently circular RNA ∼1kb genome...

Lupus Tracked to Changes in a Single Gene That Tames The Immune System Led by the Max Planck Institute for Infection Biology in Germany, the team discovered that a group of proteins called the BORC complex is needed to properly break down a protein called toll-like receptor 7 (TLR7). TLR7...

Abstract Hyperactive TLR7 signaling has long been appreciated as driver of autoimmune disease in mouse models. Recently, gain-of-function mutations in TLR7 were identified as a monogenic cause of human lupus. TLR7 is an intracellular transmembrane receptor, sensing RNA breakdown products within...

This page, https://www.nhs.uk/conditions/chronic-fatigue-syndrome-cfs/, says Page last reviewed: 29 October 2021 Next review due: 29 October 2024 Perhaps what was meant on Twitter was that following the new NICE guideline the page was rewritten, as that would then seem to fit with the...