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  1. Mij

    ACE2-dependent and -independent SARS-CoV-2 entries dictate viral replication and inflammatory response during infection, 2024, Tianhao Duan et al

    Why SARS-CoV-2 elicits mild symptoms at first but then, for a subset of patients, turn potentially fatal a week or so after infection? A recent study showed that distinct stages of illness correspond with the coronavirus acting differently in 2 different populations of cells.
  2. Mij

    ACE2-dependent and -independent SARS-CoV-2 entries dictate viral replication and inflammatory response during infection, 2024, Tianhao Duan et al

    Abstract Excessive inflammation is the primary cause of mortality in patients with severe COVID-19, yet the underlying mechanisms remain poorly understood. Our study reveals that ACE2-dependent and -independent entries of SARS-CoV-2 in epithelial cells versus myeloid cells dictate viral...
  3. Mij

    The causes that aren't genetic or pathogenic

    There was an outbreak of EBV in my area in 1991 and 15 separate people in the same neighbourhood developed MS. I developed M.E in 1991.
  4. Mij

    Review The gastrointestinal microbiota in the development of ME/CFS: a critical view and potential perspectives, 2024, Andreas Stallmach et al

    Conclusion In patients with ME/CFS, various studies have yielded inconclusive results regarding changes in the gastrointestinal processes where microbiota is involved. Whether these divergent findings are due to different molecular phenotypes of patients with ME/CFS remains speculative...
  5. Mij

    Complete remission with histamine blocker in a patient with intractable hyperadrenergic postural orthostatic tachycardia syndrome secondary to PASC

    Full Title Complete remission with histamine blocker in a patient with intractable hyperadrenergic postural orthostatic tachycardia syndrome secondary to long coronavirus disease syndrome, 2024, Gonzalez-Alvarez et al Abstract The COVID-19 pandemic caused by the novel severe acute respiratory...
  6. Mij

    Millimeter-scale magnetic implants paired with a fully integrated wearable device for wireless biophysical and biochemical sensing, 2024, JI WAN et al

    Abstract Implantable sensors can directly interface with various organs for precise evaluation of health status. However, extracting signals from such sensors mainly requires transcutaneous wires, integrated circuit chips, or cumbersome readout equipment, which increases the risks of infection...
  7. Mij

    News from Canada

    Naturopathic doctors aren't the solution to primary care: doctors, health experts Amid a family doctor shortage in Canada, many naturopathic doctors position themselves as a solution, arguing that they have the training to be a patient’s primary care provider. That’s raising alarm among...
  8. Mij

    New 'Exercise Pill' Could Induce Fitness Benefits Without Exercise

    Caffeine gives me a short boost but I feel an exhaustion 3 hours later. On days that I drink coffee I'm unable to do my walking routine in the evening
  9. Mij

    Deep phenotyping of post-infectious myalgic encephalomyelitis/chronic fatigue syndrome, 2024, Walitt et al

    Merged thread Landmark Study Confirms Chronic Fatigue Syndrome Is 'Unambiguously Biological' News but not new news https://www.sciencealert.com/landmark-study-confirms-chronic-fatigue-syndrome-is-unambiguously-biological
  10. Mij

    New 'Exercise Pill' Could Induce Fitness Benefits Without Exercise

    A synthetic ERR agonist alleviates metabolic syndrome, 2024 https://pubmed.ncbi.nlm.nih.gov/37739806/
  11. Mij

    New 'Exercise Pill' Could Induce Fitness Benefits Without Exercise

    It's back in the news again. Scientists in the US claim to have boiled down some of the health benefits of exercise into a swallowable pill. The novel drug is in the very early stages of development, but in initial experiments on rodents, the medicine appears to tap into a natural metabolic...
  12. Mij

    The associations of HSV and varicella zoster virus infection with dementia: a nationwide retrospective cohort study, 2024, Eunhae Shin et al

    Abstract Background In this study, the risk of dementia in patients with a history of herpes simplex virus (HSV) or varicella zoster virus (VZV) infection was evaluated. Methods This nationwide cohort study used data from the Korean National Health Insurance Service collected between 2006 and...
  13. Mij

    Serologic Response to the Epstein-Barr Virus Peptidome and the Risk for Multiple Sclerosis, 2024, Marianna Cortese, MD, PhD et al

    Key Points Question Do individuals with multiple sclerosis (MS) have antibody titers against 1 or more Epstein-Barr virus (EBV) peptides that do not commonly generate an antibody response in healthy individuals of the same age, sex, and race and ethnicity? Findings In this nested...
  14. Mij

    News from Australia

    Shingles cases are increasing in New South Wales. Experts say COVID might be why https://www.abc.net.au/news/2024-03-21/shingles-cases-increasing-nsw-covid-rise/103600746
  15. Mij

    2 doctors told him he had a fatal disease and wouldn't live until Christmas. They were wrong

    ALS is difficult to diagnose because the initial symptoms can be very similar to other diseases, according to the ALS Society of Canada. He noted it can take upwards of 18 months from the onset of symptoms to come to a diagnosis. "I'm sorry to say this: Family physicians should never be...
  16. Mij

    Renaming schizophrenia: a Japanese perspective, 2006

    There is evidence that stigma-related attitudes toward people with mental health and mental illness remain relatively high in Japan. Japan still has one of the highest suicide rates among high-income OECD countries. Cultural attitudes towards suicide in Japan have been described as "tolerant"...
  17. Mij

    CDC Multi-site Study: Heterogeneity in ME/CFS Illness Measures Not Explained by Clinical Practice, 2024, Unger et al

    Merged - this is about an article discussing the paper that is the subject of this thread A new CDC-funded paper includes criteria that may be leading to inaccurate prevalence rates The stock photo . . . https://www.medpagetoday.com/opinion/second-opinions/109274?trw=no
  18. Mij

    Paul Garner on Long Covid and ME/CFS - BMJ articles and other media.

    Well I have to say that I saw fear in his eyes when I watched his interviews on 2 separate US news channel a few of years during his Covid infection.
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