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    The High Cost of Low-Grade Inflammation: Fatigue as a Consequence of Reduced Cellular-Energy Availability and Non-adaptive Energy Expenditure (2018)

    Title altered slightly to fit but left untouched below. https://www.ncbi.nlm.nih.gov/pubmed/29755330 https://www.frontiersin.org/articles/10.3389/fnbeh.2018.00078/full
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    Australian budget delivers for science facilities and medical research

    You can bet that approximately $0 of that will go to research for ME/CFS.
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    Chronic fatigue syndrome and idiopathic intracranial hypertension: Different manifestations of the same disorder of intracranial, 2017, Higgins et al

    Can't you just get around that by using different DNS servers? That works in Australia and is very easy to do.
  4. H

    Fecal transplants not effective in patients with both IBS and ME

    The full paper conveniently tries to palm those treatment failures off as their IBS being psychosomatic.
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    Blog: Ill versus disabled – is there a distinction between the two?

    There's also quite a difference between people with mild ME and those on the more severe end of the spectrum. People with mild ME (still able to do some work and have a social life, participate in life events and gatherings) are much more similar to regular disabled than they are to those that...
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    Ron Davis Q and A -Massachusetts- March 2018

    How do they intend to treat the "central control system" if not with a new drug? Suramin?
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    Unprecedented study identifies 44 genetic risk factors for major depression

    More at the link: https://medicalxpress.com/news/2018-04-unprecedented-genetic-factors-major-depression.html
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    Integration of DNA methylation & health scores identifies subtypes in myalgic encephalomyelitis/chronic fatigue syndrome (2018)

    https://www.ncbi.nlm.nih.gov/pubmed/29692205 https://www.futuremedicine.com/doi/10.2217/epi-2017-0150
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    Publisher Gets Carte Blanche to Seize New Sci-Hub Domains

    Well, The Pirate Bay is still around after all these years of similar intervention.
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    Whole-exome sequencing uncovers oxidoreductases DHTKD1 and OGDHL as linkers between mitochondrial dysfunction and eosinophilic esophagitis (2018)

    For EoE? No. It's diagnosed via esophageal biopsy collected during endoscopy. I think it's pretty routine to test for EoE now but I could be wrong, maybe they only test if someone is symptomatic.
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    Whole-exome sequencing uncovers oxidoreductases DHTKD1 and OGDHL as linkers between mitochondrial dysfunction and eosinophilic esophagitis (2018)

    I thought some others might also find this interesting. I have EoE and my EoE and stomach problems flare from exertion and it's becoming pretty obvious it's playing quite a big role in my disease. I've also suspected that I have severe mitochondrial dysfunction in these organs but unable to...
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    Pharmacological activation of AMPK and glucose uptake in cultured human skeletal muscle cells from patients with ME/CFS (2018) Newton et al

    https://www.ncbi.nlm.nih.gov/pubmed/29654166
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    HIV-infected people are living for years, but age-related diseases set in early

    I wonder if the drug cocktail also contributes to their early demise.
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    Rituximab 'causes impaired immune function, Griffith study says'

    @Andy I just edited to clarify.
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    Rituximab 'causes impaired immune function, Griffith study says'

    I googled very briefly after seeing this media release and noticed this different publication about NK cells and Rituximab below. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5024429/
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    Rituximab 'causes impaired immune function, Griffith study says'

    It would most certainly have to be the latter. They recruited in the past for studies involving in vitro drug testing but as far as I'm aware haven't recruited for an actual in vivo trial of any kind.
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    Rituximab 'causes impaired immune function, Griffith study says'

    Wish they wouldn't do these media releases until the publication is actually available.
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    Balance deficits in Chronic Fatigue Syndrome with and without Fibromyalgia (2018) Natelson et al

    https://www.ncbi.nlm.nih.gov/pubmed/29562557
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    Trial of CT38 for ME/CFS by Cortene Inc.: big claims being made...

    I doubt we'll have any truly successful clinical trials until we have sub-types but hopefully some of these failed trials can provide data that will help tease them out.
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