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Unexpected detection of SARS-CoV-2 antibodies in the prepandemic period in Italy

Discussion in 'Epidemics (including Covid-19, not Long Covid)' started by Hoopoe, Nov 15, 2020.

  1. Hoopoe

    Hoopoe Senior Member (Voting Rights)

    Messages:
    5,254
    https://journals.sagepub.com/doi/abs/10.1177/0300891620974755?journalCode=tmja
     
    Hoopoe, Nov 15, 2020
    #1
    spinoza577, Simon M, Michelle and 6 others like this.
  2. Snow Leopard

    Snow Leopard Senior Member (Voting Rights)

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    3,827
    Location:
    Australia
    Serological tests like this have known limitations in specificity and there is also a risk of contamination, however unlikely.

    But the biggest limitation is the fact they didn't bother to confirm with PCR testing - without doing so, this study is sloppy and unconvincing.

    If the study was published in a preprint in March/April and the authors indicated they would shortly followup with PCR testing, I'd give them the benefit of the doubt, but that wasn't the case.
     
    Snow Leopard, Nov 15, 2020
    #2
    Starlight, Simon M, Michelle and 8 others like this.

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