Tuberculosis Vaccine as a cure for diabetes, multiple sclerosis

[Webdog]

http://fortune.com/2018/06/21/tuberculosis-vaccine-reverse-juvenile-diabetes-study-shows/

Tuberculosis Vaccine Could Reverse Type 1 Diabetes, Study Shows

The causes of Type 1 diabetes can be significantly reversed over several years with just two injections of a common tuberculosis vaccine injected a few weeks apart, researchers at Massachusetts General Hospital (MGH) announced Thursday in a paper published in the journal Nature.

Researchers found a substantial reduction in the blood-sugar marker HbA1c that is used to diagnose diabetes. All subjects with diabetes who received the vaccine had a 10% reduction after three years and 18% after four years, bringing them below the cutoff point for a clinical diagnosis. Those subjects followed for a full eight years retained most of the reduction.

Based on initial mice tests, researchers expected the vaccine would prompt regeneration of the pancreas, which produces insulin. Instead, they write in their paper, a form of white blood cells starts to metabolize sugar more aggressively—10 to 20 times as much as they normally consume.

 

[Mij]

Merged thread
A repurposed TB vaccine shows early promise against diseases like diabetes and MS

Around the world, volunteers are getting a vaccine developed to prevent tuberculosis in studies that have nothing to do with TB. Called Bacillus Calmette-Guérin, or BCG, the shot is being tested as a treatment for type 1 diabetes, Alzheimer’s disease, multiple sclerosis and even COVID-19.

https://www.sciencenews.org/article/bcg-tb-vaccine-diseases-diabetes-multiple-sclerosis

 

[James Morris-Lent]

I dunno, this has been used for bladder cancer for decades (FDA approval 1990). So while the idea of using it for things other than TB is fairly old, it's not been approved for anything else (I'm not sure if it's used at all in other cancers?). My money is on hype but anything is possible.

Really lazy reporting here on cohort studies showing lower rates of lung cancer or Alzheimer's in different studies. This is an obvious form of p-hacking. Like, yeah, you give people a shot or placebo and decades later tally up who got what diseases... well no shit that among *all* diseases there are a few that are different between groups. Let me know if one group lived way longer or had fewer cancers overall or became way more wealthy or something.

 

[Mithriel]

I got the BCG after I had ME. Did not help, obviously

 

[Jaybee00]

Merged thread

NYU withdraws from BCG vaccine trial for Type 1 diabetes

Some are suggesting that this vaccine is also useful for *another* condition

https://www.nytimes.com/2023/01/20/...LTLQoASaXhCznm7iOSqAp8HwsVl5Ie&smid=share-url

 

[Jaybee00]

 

[Hutan]

See also this discussion thread
BCG Tuberculosis vaccine - and related testing - Epic Genetics

 

[hibiscuswahine]

Science by twitter “experts”. Vaccinating us. What could possibly go wrong? (all the people who got ME triggered by other vaccines and put into severe disability)