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Treatment of Long-Haul COVID Patients With Off-Label Acyclovir, 2023, Emily R German et al

Discussion in 'Long Covid research' started by Mij, Apr 22, 2023.

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  1. Mij

    Mij Senior Member (Voting Rights)

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    8,326
    Abstract
    The SARS-CoV-2 virus (COVID-19) became a global pandemic in March 2020. This novel, highly infectious virus caused millions of infections and deaths around the world. Currently, there are few medications that are available for the treatment of COVID-19. Those affected are most commonly given supportive care, with some experiencing symptoms for months.

    We report a series of four cases depicting the successful use of acyclovir in the treatment of the virus SARS-CoV-2 in patients with long-haul symptoms, especially those in the realm of encephalopathy and neurological problems. Treatment with acyclovir in these patients resolved their symptoms and lowered their IgG and IgM titers, supporting the use of acyclovir as a safe and effective treatment for COVID-19 neurologic symptoms.

    We suggest the use of the antiviral medication, acyclovir, as a treatment for patients with long-term symptoms and unusual presentations of the virus, such as encephalopathy or coagulopathy.

    https://www.cureus.com/articles/128...ul-covid-patients-with-off-label-acyclovir#!/
     
    Mij, Apr 22, 2023
    #1
    Peter Trewhitt, Hutan and Arnie Pye like this.
  2. Hutan

    Hutan Moderator Staff Member

    Messages:
    26,926
    Location:
    Aotearoa New Zealand
    Here's a taste of the case studies:
    I find the certainty in the abstract really remarkable. Just maybe acyclovir in the early stages of an infection might reduce ongoing symptoms. But, there's really nothing here to suggest that anything is going on but resolution of symptoms over time.

    There must be a problem in the way physicians are taught, that so many of them end up leaping to the conclusion that the treatments that they have identified make a material difference, despite the lack of evidence.

    This paper was supposedly peer reviewed. Not only does it present leaps of logic, but there are still typos.
     
    Last edited: Apr 23, 2023
    Hutan, Apr 23, 2023
    #2
    alktipping, Peter Trewhitt, Mij and 5 others like this.
  3. Hubris

    Hubris Senior Member (Voting Rights)

    Messages:
    315
    With every passing year the standards in medicine keep getting worse. How is that even possible? I can't think of another field where professionals are so apathetic that they don't care at all about improving and keep spiraling down. Some professions change for the worse, but medicine did not even truly change, it just keeps becoming more and more decadent. Sometimes i wonder if doctors like to call everyone mentally ill simply because they are projecting.
     
    Hubris, Apr 23, 2023
    #3
    alktipping and Peter Trewhitt like this.

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