The role of infections in multiple sclerosis - Marrodan,Alessandro,Farez,Correale Jun 2019

Sly Saint

Sly Saint

Senior Member (Voting Rights)
Abstract
Several lines of evidence suggest that multiple sclerosis (MS), like other autoimmune diseases, may be triggered by microbial infections. Pathogens associated with development or exacerbation of MS include bacteria, such as Chlamydia pneumoniae, Staphylococcus aureus-produced enterotoxins that function as superantigens, and viruses of the Herpesviridae (Epstein-Barr virus and human herpes virus 6) and human endogenous retrovirus families. However, to date, no single pathogen has been accepted as causal agent. In addition, common upper respiratory, gastrointestinal, and urogenital tract infections have also been associated with MS exacerbations. Although evidence of an infectious etiology as cause of MS in humans remains inconclusive, microbial agents may modulate the neuroimmunological system of genetically susceptible individuals. Decoding the epidemiological contribution of different microorganisms to MS, along with their pathogenic mechanisms, may help develop new treatment strategies and prevent relapses.
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https://www.ncbi.nlm.nih.gov/pubmed/30638421

https://sci-hub.tw/10.1177/1352458518823940
 
InitialConditions said:
i think at some point the medical community has to wake up and realise that once an initial infection is gone, even from 'trivial' pathogens and viruses, that's not the end of the story....
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Seriously bizarre that an organism whose sole purpose is hijacking the cellular process of its host can be considered inconsequential unless it is growing out of control. As if all those proteins and RNA strands changing gene expression had no effect. Don't need to destroy cells to disrupt their function.

Basically waiting for the moment of a rediscovery of the germ theory of disease. Meanwhile we're stuck with a neo-Freudian golden age of pseudoscience. Good grief this is embarrassing.
 
It was predicted, by a man, who wrote a book, and then some more books, and then, surprisingly, apparently 2 more books after he died, about another man, who predicted the collapse of human civilisation due to exactly the things that are happening now. Due to the 'we know everything apart from a few irrelevant details' attitude and the lack of research being anything other than a money making, career building endeavour. Due to the fall of 'science', and people's preference for not fixing things that have broken, and not being interested in learning how to.

The mans name, the second one, the fictional one, was Harry Seldon. No idea who the first guy was, someone famous, but currently deceased. I may ask him if I ever meet him, what his name was.

The main error in his prediction was that humanity would have had tens of thousands of years of galactic civilisation before it happened, and thus his suggested solution will not work.

So, we is all turkeys, on Christmas day, in homes where people eat stuffed turkey, on Christmas day.

I do find it surprising, that people seem surprised, astonished, and disbelieving, when it is asserted that an organism whose main effect on humans is to make them ill, is found to make them ill.
 
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