Andy
Senior Member (Voting rights)
Abstract
Objectives
Pediatric disorders of gut-brain interaction (DGBI) often co-occur with a variety of mental health conditions. This analysis examines the impact of a brief cognitive behavioral program (ADAPT; Aim to Decrease Anxiety and Pain Treatment) targeting pain and anxiety in youth with DGBI and comorbid mental health diagnoses.Study Design
This secondary analysis of a clinical trial includes participants between the ages of 9-14 with DGBI, randomized to ADAPT plus medical treatment as usual (TAU), or TAU alone. Participants completed the Anxiety Disorder Interview Schedule for DSM-IV, Child Version (ADIS-IV-C) to determine if they met criteria for a mental health diagnosis at baseline and at post assessment 8 weeks later. Analysis of Covariance (ANCOVA)-style logistic regression models were used to assess whether ADAPT+TAU had an impact on mental health diagnoses compared to TAU alone.Results
ADAPT+TAU was associated with a lower posttest rate of generalized anxiety disorder (GAD) compared to TAU (26.4% vs 46.1%, OR = 3.11, 95% CI = [1.03, 9.41].) Although additional diagnoses trended in similar directions, no other rates of diagnoses across other mental health conditions met the threshold for significance at post-test.Conclusion
ADAPT is associated with reductions in GAD diagnoses in youth with DGBI. Although not a target of ADAPT, there appeared to be a generalization of treatment effects on other mental health conditions, but larger controlled studies are needed.Paywall