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The Human Cell Atlas: making ‘cell space’ for disease, 2019, Ponting

Discussion in 'Health News and Research unrelated to ME/CFS' started by Andy, Jan 15, 2019.

  1. Andy

    Andy Committee Member (& Outreach when energy allows)

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    Open access at http://dmm.biologists.org/content/early/2019/01/14/dmm.037622
     
  2. Jonathan Edwards

    Jonathan Edwards Senior Member (Voting Rights)

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    I hate to be a killjoy but I think we used to do this forty years ago. It was called histochemistry done by people with a solid histological training. All the complex pattern identification functions were done by what Turing called 'computers' - human brains. They are quite good at it! We sorted out RA by looking at complex biochemical patters across a cell space called a microscope slide. That in the end allowed us to work out a system dynamics for a disease with 55 linked steps.
     
  3. Barry

    Barry Senior Member (Voting Rights)

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    Is this a clue? Presumably analysis of such large numbers would only be feasible using modern computing power?
     
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  4. Jonathan Edwards

    Jonathan Edwards Senior Member (Voting Rights)

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    A histologist's eye regularly analyses tens of millions of cells without even thinking.
     
  5. Snowdrop

    Snowdrop Senior Member (Voting Rights)

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    I just came upon this separately from this thread.
    Here is a link to the project.

     
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