(I'm not entirely sure where to post this since it's neither biomedical nor psychosocial research...) The Economic Impacts of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome in an Australian Cohort Shara Close, Sonya Marshall-Gradisnik, Joshua Byrnes, Peter Smith, Son Nghiem and Don Staines https://www.frontiersin.org/articles/10.3389/fpubh.2020.00420/full So much for the massive cost-savings of biopsychosocial disease denial. Ignore opportunity cost at great peril. Simple solutions to complex problems are almost always wrong. Australia's GDP is ~1.7% of the world's GDP. Depending on how parity costs can be extrapolated in various economies, this would represent economic losses on the order of $800,000,000,000 ($800B) per year. Even very conservative underestimations place this at direct economic losses at well above $1 trillion per decade. The BPS model of illness is not only a humanitarian and scientific disaster, it is also an economic one. Quite likely the most expensive failure of expertise in world history.