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Successful Treatment of [ME/CFS] with Chronic Febricula Using the Traditional Japanese Medicine Shosaikoto, 2019, Numata et al

Discussion in 'Alternative Therapies' started by Andy, Sep 20, 2019.

  1. Andy

    Andy Committee Member & Outreach

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    For what it's worth.
    Open access, https://www.jstage.jst.go.jp/article/internalmedicine/advpub/0/advpub_3218-19/_article
     
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  2. adambeyoncelowe

    adambeyoncelowe Senior Member (Voting Rights)

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    From Wikipedia:
     
    Last edited: Sep 20, 2019
  3. Trish

    Trish Moderator Staff Member

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    I had to look up febricula. It sounds scary, but it's just a fancy word for a slight fever.
     
  4. Cheshire

    Cheshire Moderator Staff Member

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    Case report... Maximizes all the biases and doesn't prove anything.
     
    Last edited: Sep 20, 2019
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  5. Trish

    Trish Moderator Staff Member

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    I'm surprised they write up a single case like this for a medical journal. Why not do a pilot study before publishing?
     
  6. Peter Trewhitt

    Peter Trewhitt Senior Member (Voting Rights)

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    There is a place for single case studies, as long as any conclusions do not go beyond what the evidence can support. However the best you can conclude here is sugestions further investigation.
     
  7. Snow Leopard

    Snow Leopard Senior Member (Voting Rights)

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    Most likely explanation is that it is a coincidence, with natural remission. I'd be very sceptical of anything less than a blinded pilot study.
     
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  8. Forbin

    Forbin Senior Member (Voting Rights)

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    Febricula sounds like Dracula's less popular third cousin. :)
     
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  9. mariovitali

    mariovitali Senior Member (Voting Rights)

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    Here is the scihub link :

    https://scihub.wikicn.top/10.2169/internalmedicine.3218-19


    I went through entries on PUBMED for shosaikoto. Scary and interesting at the same time. Anything related to Liver disease and Hepatic fibrosis is of personal interest (i presented a few cases of patients with significant liver fibrosis on my presentation at the CureME team and asked whether such cases warrant further investigation).

    Some studies show a potential antifibrotic effect of shosaikoto. Here is one of them

    https://pubmed.ncbi.nlm.nih.gov/10759225/

     
    Last edited: Sep 10, 2020
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