Successful Treatment of [ME/CFS] with Chronic Febricula Using the Traditional Japanese Medicine Shosaikoto, 2019, Numata et al

Discussion in 'Other treatments' started by Andy, Sep 20, 2019.

  1. Andy

    Andy Retired committee member

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    For what it's worth.
    Open access, https://www.jstage.jst.go.jp/article/internalmedicine/advpub/0/advpub_3218-19/_article
     
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  2. adambeyoncelowe

    adambeyoncelowe Senior Member (Voting Rights)

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    From Wikipedia:
     
    Last edited: Sep 20, 2019
  3. Trish

    Trish Moderator Staff Member

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    I had to look up febricula. It sounds scary, but it's just a fancy word for a slight fever.
     
  4. Cheshire

    Cheshire Senior Member (Voting Rights)

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    Case report... Maximizes all the biases and doesn't prove anything.
     
    Last edited: Sep 20, 2019
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  5. Trish

    Trish Moderator Staff Member

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    I'm surprised they write up a single case like this for a medical journal. Why not do a pilot study before publishing?
     
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  6. Peter Trewhitt

    Peter Trewhitt Senior Member (Voting Rights)

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    There is a place for single case studies, as long as any conclusions do not go beyond what the evidence can support. However the best you can conclude here is sugestions further investigation.
     
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  7. Snow Leopard

    Snow Leopard Senior Member (Voting Rights)

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    Most likely explanation is that it is a coincidence, with natural remission. I'd be very sceptical of anything less than a blinded pilot study.
     
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  8. Forbin

    Forbin Senior Member (Voting Rights)

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    Febricula sounds like Dracula's less popular third cousin. :)
     
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  9. mariovitali

    mariovitali Senior Member (Voting Rights)

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    Here is the scihub link :

    https://scihub.wikicn.top/10.2169/internalmedicine.3218-19


    I went through entries on PUBMED for shosaikoto. Scary and interesting at the same time. Anything related to Liver disease and Hepatic fibrosis is of personal interest (i presented a few cases of patients with significant liver fibrosis on my presentation at the CureME team and asked whether such cases warrant further investigation).

    Some studies show a potential antifibrotic effect of shosaikoto. Here is one of them

    https://pubmed.ncbi.nlm.nih.gov/10759225/

     
    Last edited: Sep 10, 2020
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