Stem Cell Therapy for Chronic Fatigue Syndrome: A Promising Approach, 2024, Vinski

Dolphin

Senior Member (Voting Rights)
https://jws.rivierapublishing.id/index.php/jws/article/view/1231

Stem Cell Therapy for Chronic Fatigue Syndrome: A Promising Approach
Authors
  • Deby Susanti Pada Vinski Pada Vinski
  • Svetlana TrofimovaInstitute of Bioregulation and Gerontology, St. Petersburg
  • Jaime Rodriguez QuintosaEfhre International University, Barcelona
  • Andi Kurniawan NugrohoUniversitas Semarang, Semarang
  • CA SchroeterKastanienh of Clinic, Köln Junkersdorf
  • Stevan JovanovicInstitut Médical de Champel, Geneva
DOI:
https://doi.org/10.58344/jws.v3i11.1231
Keywords:
chronic fatigue syndrome, immunomodulation, mesenchymal stem cells, regenerative medicine, stem cell therapy

Abstract

Chronic Fatigue Syndrome (CFS), or Myalgic Encephalomyelitis (ME), is a debilitating condition marked by persistent fatigue, cognitive dysfunction, and chronic pain, severely affecting quality of life.

This study explores the potential of mesenchymal stem cell (MSC) therapy as an innovative treatment for CFS.

Using a qualitative descriptive design and case studies, data were gathered through interviews, medical record reviews, and observations of patients undergoing MSC therapy.

The findings revealed significant improvements in fatigue, cognitive function, and physical well-being, with participants reporting better memory, concentration, reduced pain, and improved daily functioning.

While some sleep disturbances persisted, their severity was reduced.

These results highlight the potential of MSC therapy to alleviate CFS symptoms and enhance quality of life.

Despite its promise, challenges such as high costs, regulatory hurdles, and the need for standardized protocols persist.

Further research is required to confirm long-term efficacy and safety, contributing to the growing evidence for regenerative medicine in treating chronic conditions like CFS.
 
From the wiki: "There is also growing concern about the marketing and application of unapproved MSCs and mesenchymal stem cells that lack rigorous data to back up these clinical uses into patients by for-profit clinics.[70][71]"

I wonder if "promising" is closely related to political promises (ie. not worth much).
 
This looks like a group of quacks doing a bit of communal marketing.
I have no idea what they even mean by mesenchymal stem cell therapy. We all have plenty of mesenchymal stem cells so it seems unlikely that a few more would make much difference.
 
The first citations I decided to look at have no relevance to the sentence they follow. Neither one mentions stem cells.
Prior studies have examined the use of MSCs for various inflammatory and autoimmune diseases, revealing their potential to modulate immune responses and repair tissue damage. MSCs have been shown to inhibit the release of pro-inflammatory cytokines and promote tissue repair, which could benefit CFS patients with similar inflammatory profiles (Hoban et al., 2015; Tomas et al., 2017). However, research specifically investigating MSC therapy for CFS remains limited, with findings that are preliminary and in need of further validation (Jason & Sunnquist, 2018; Tomas et al., 2017).

Jason, L. A., & Sunnquist, M. (2018). The development of the DePaul Symptom Questionnaire: Original, expanded, brief, and pediatric versions. Frontiers in Pediatrics, 6, 409729.

Tomas, C., Brown, A., Strassheim, V., Elson, J., Newton, J., & Manning, P. (2017). Cellular bioenergetics is impaired in patients with chronic fatigue syndrome. PloS One, 12(10), e0186802.
 
Some of the authors also published Stem Cell Therapy for Men's Vitality, and it similarly has great promise but there is too little research.

Maybe they Googled 'unsolved challenges in medicine' and took it from there.
 
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