https://jws.rivierapublishing.id/index.php/jws/article/view/1231 Stem Cell Therapy for Chronic Fatigue Syndrome: A Promising Approach Authors Deby Susanti Pada Vinski Pada Vinski Svetlana TrofimovaInstitute of Bioregulation and Gerontology, St. Petersburg Jaime Rodriguez QuintosaEfhre International University, Barcelona Andi Kurniawan NugrohoUniversitas Semarang, Semarang CA SchroeterKastanienh of Clinic, Köln Junkersdorf Stevan JovanovicInstitut Médical de Champel, Geneva DOI: https://doi.org/10.58344/jws.v3i11.1231 Keywords: chronic fatigue syndrome, immunomodulation, mesenchymal stem cells, regenerative medicine, stem cell therapy Abstract Chronic Fatigue Syndrome (CFS), or Myalgic Encephalomyelitis (ME), is a debilitating condition marked by persistent fatigue, cognitive dysfunction, and chronic pain, severely affecting quality of life. This study explores the potential of mesenchymal stem cell (MSC) therapy as an innovative treatment for CFS. Using a qualitative descriptive design and case studies, data were gathered through interviews, medical record reviews, and observations of patients undergoing MSC therapy. The findings revealed significant improvements in fatigue, cognitive function, and physical well-being, with participants reporting better memory, concentration, reduced pain, and improved daily functioning. While some sleep disturbances persisted, their severity was reduced. These results highlight the potential of MSC therapy to alleviate CFS symptoms and enhance quality of life. Despite its promise, challenges such as high costs, regulatory hurdles, and the need for standardized protocols persist. Further research is required to confirm long-term efficacy and safety, contributing to the growing evidence for regenerative medicine in treating chronic conditions like CFS.
From the wiki: "There is also growing concern about the marketing and application of unapproved MSCs and mesenchymal stem cells that lack rigorous data to back up these clinical uses into patients by for-profit clinics.[70][71]" I wonder if "promising" is closely related to political promises (ie. not worth much).
Worth noting that nominee for Secretary of Health, RFK Jr, is a supporter of these “therapies”, despite them underperforming RCTs, and claims that they have been “unfairly dismissed” by the FDA.
This looks like a group of quacks doing a bit of communal marketing. I have no idea what they even mean by mesenchymal stem cell therapy. We all have plenty of mesenchymal stem cells so it seems unlikely that a few more would make much difference.
The first citations I decided to look at have no relevance to the sentence they follow. Neither one mentions stem cells. Jason, L. A., & Sunnquist, M. (2018). The development of the DePaul Symptom Questionnaire: Original, expanded, brief, and pediatric versions. Frontiers in Pediatrics, 6, 409729. Tomas, C., Brown, A., Strassheim, V., Elson, J., Newton, J., & Manning, P. (2017). Cellular bioenergetics is impaired in patients with chronic fatigue syndrome. PloS One, 12(10), e0186802.
Some of the authors also published Stem Cell Therapy for Men's Vitality, and it similarly has great promise but there is too little research. Maybe they Googled 'unsolved challenges in medicine' and took it from there.
