Science in the News - HARVARD Kenneth C. Griffin Blog by Ya'el Courtney Quote: The first well-documented observation of PAIS was Post-Polio Syndromein the 1870s, where people developed muscular degeneration and weakness 15-40 years after infection with poliomyelitis. Since then, PAIS has been noted after infection by many viruses – from influenza to the common cold to Epstein-Barr Virus (EBV) (also known as ‘mono’ or glandular fever). It was not until the 1980s that doctors began to recognize similar chronic conditions as serious medical problems, and a new diagnosis was born: myalgic encephalomyelitis/chronic fatigue syndrome, or ME/CFS. However, attempts to identify a single infectious agent as the cause of ME/CFS have been unsuccessful, complicating efforts to find a cure. This brings us to a compelling proposition: could ME/CFS be more accurately described as a spectrum of post-acute infectious syndromes? This perspective suggests that various infectious agents could trigger a prolonged, systemic response, manifesting in remarkably consistent symptoms across different cases. The COVID-19 pandemic has provided a unique opportunity to explore this hypothesis, as the similarities between long COVID and ME/CFS are striking. https://sitn.hms.harvard.edu/flash/...-unexplained-post-acute-infectious-syndromes/
I think this is a fairly good, though superficial and uncritical, summary of what is known and not known based on a few of the main US sources of information, NIH, CDC, Mayo clinic. It's written by a PhD student.
I like it, its a good overview. Gone are the days of struggling to have anyone believe you when you say you have a recurring virus.
