Review: Astaxanthin: A Potential Mitochondrial-Targeted Antioxidant Treatment in Diseases and with Aging, 2019, Sztretye et al

[Andy]

Oxidative stress is characterized by an imbalance between prooxidant and antioxidant species, leading to macromolecular damage and disruption of redox signaling and cellular control. It is a hallmark of various diseases including metabolic syndrome, chronic fatigue syndrome, neurodegenerative, cardiovascular, inflammatory, and age-related diseases. Several mitochondrial defects have been considered to contribute to the development of oxidative stress and known as the major mediators of the aging process and subsequent age-associated diseases. Thus, mitochondrial-targeted antioxidants should prevent or slow down these processes and prolong longevity. This is the reason why antioxidant treatments are extensively studied and newer and newer compounds with such an effect appear. Astaxanthin, a xanthophyll carotenoid, is the most abundant carotenoid in marine organisms and is one of the most powerful natural compounds with remarkable antioxidant activity. Here, we summarize its antioxidant targets, effects, and benefits in diseases and with aging.

Open access, https://www.hindawi.com/journals/omcl/2019/3849692/

 

[erin]

I have used astaxanthin, not had any improvement in any of my symptoms. It was also very difficult to digest for me.

 

[Mij]

I took this for 6 months because my beta-carotene and alpha-carotene markers were in very low range. psssf- nothing.

How are we supposed to even know if it's helping? All my antioxidants are very low.

My new thing is Japanese cheesecake. I eat it and feel better. Done.

 

[Jonathan Edwards]

I think that would make anyone feel better, including me. I must go out and get some.

 

[Hoopoe]

My new thing is Japanese cheesecake. I eat it and feel better. Done.

Have you considered creating a new therapy, the Cheesecake Process? I think it will be a fantastic and delicious success. Very high scores on cake satisfaction questionnaires.

 

[Mij]

CBT- Cheesecake Behavioral Therapy.

 

[rvallee]

View attachment 9395

I think that would make anyone feel better, including me. I must go out and get some.

Absolutely guaranteed to be more effective than TAU.

To be fair, "nothing" is not exactly a high bar but that is one thing cheesecake can definitely do. Just... skip the long-term follow-up.

 

[Mij]

I think that would make anyone feel better, including me. I must go out and get some.[/QUOTE]

Healthy controls have always played a vital role.

 

[Jonathan Edwards]

Healthy controls have always played a vital role.

I am afraid I am long since disqualified.

 

[Barry]

I am afraid I am long since disqualified.

'Liked' in the sense of sorry to hear that.