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Reduced parasympathetic reactivation during recovery from exercise in(ME)/(CFS) - 2015 J. Van Oosterwijck et al

Discussion in 'BioMedical ME/CFS Research' started by Sly Saint, Nov 1, 2020.

  1. Sly Saint

    Sly Saint Senior Member (Voting Rights)

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    Not a new study.

    Reduced parasympathetic reactivation during recovery from exercise in myalgic encephalomyelitis (ME)/chronic fatigue syndrome (CFS)

    2015

    https://www.physiotherapyjournal.com/article/S0031-9406(15)02014-3/abstract


    @PhysiosforME you might be interested in these authors research (see also Polli).
     
  2. Snow Leopard

    Snow Leopard Senior Member (Voting Rights)

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    Heart rate (beat to beat) variation is quite nonspecific and doesn't necessarily suggest any abnormal pathology at all.

    In particular, the restoration of regular HRV in healthy people occurs more rapidly in those with higher levels of fitness. As the above study did not control for fitness, the effect may simply be an artifact of lower fitness. The abstract is also from a conference, rather than a proper peer-reviewed manuscript, so key details of the methodology and results are missing (like a visualisation of change over time).

    The abstract of the following review makes some clear points:
    Cardiac parasympathetic reactivation following exercise: implications for training prescription
    https://pubmed.ncbi.nlm.nih.gov/23912805/
    doi:10.1007/s40279-013-0083-4

    With regards to metaboreflex stimluation, they state:
    The described baroreflex stimulation requires post-exercise hypervolmemia, but I'm not convinced this is a factor in ME/CFS. The increased difficulty in achieving similar VO2Peak on a second CPET after 24 hours seems to also contradict this.

    There is also suggestion that delayed "parasympathetic reactivation" is due to centrally acting chemo/metaboloreflex:

    Effect of Acute Hypoxia on Post-Exercise Parasympathetic Reactivation in Healthy Men
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429061/
     

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