Review Prevalence of mental health conditions and brain fog in people with long COVID, 2024, van der Feltz-Cornelis et al

Discussion in 'Long Covid research' started by Amw66, May 22, 2024.

  1. Amw66

    Amw66 Senior Member (Voting Rights)

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    More than a quarter of people with Covid infection develop Long Covid, new research reveals

    Don't know how accurate this is, but given the vagueness of " long COVID" as a definition , it could well be


    The study reviewed 17 studies from around the world involving more than 40,000 Long COVID patients. It was carried out in collaboration with the STIMULATE-ICP project, which is a £6.8 million NIHR-funded national research project led by University College London.


    https://www.york.ac.uk/news-and-events/news/2024/research/long-covid-fog/
     
    Last edited by a moderator: May 24, 2024
    MEMarge, Kitty, Hutan and 4 others like this.
  2. Hutan

    Hutan Moderator Staff Member

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    Prevalence of mental health conditions and brain fog in people with long COVID: A systematic review and meta-analysis - link

    Christina van der Feltz-Cornelisa,b,c,*, Fidan Turka,1, Jennifer Sweetmana,1, Kamlesh Khuntid, Mark Gabbay e, Jessie Shepherd a, Hugh Montgomery f, W. David Strain g, Gregory Y.H. Lip h, i, Dan Wootton j, k, Caroline Leigh Watkins l, m, Daniel J. Cuthbertson n, Nefyn Williams e, Amitava Banerjeec,o,p

    (Note some of those authors, such as van der Feltz-Cornelis are all over the psychosomatic literature, although occupying the contortion-requiring but increasingly common position of accepting there are physical components to 'functional' diseases. Note also the presence of David Strain in that list - he has co-authored a number of papers with van der F-C.)

    Abstract
    Objective: Long COVID can include impaired cognition (‘brain fog’; a term encompassing multiple symptoms) and mental health conditions. We performed a systematic review and meta-analysis to estimate their prevalence and to explore relevant factors associated with the incidence of impaired cognition and mental health conditions.

    Methods: Searches were conducted in Medline and PsycINFO to cover the start of the pandemic until August 2023. Included studies reported prevalence of mental health conditions and brain fog in adults with long COVID after clinically-diagnosed or PCR-confirmed SARS-CoV-2 infection.

    Findings: 17 studies were included, reporting 41,249 long COVID patients. Across all timepoints (3–24 months), the combined prevalence of mental health conditions and brain fog was 20⋅4% (95% CI 11⋅1%-34⋅4%), being lower among those previously hospitalised than in community-managed patients(19⋅5 vs 29⋅7% respectively; p = 0⋅047). The odds of mental health conditions and brain fog increased over time and when validated in- struments were used. Odds of brain fog significantly decreased with increasing vaccination rates (p = ⋅000).

    Conclusions: Given the increasing prevalence of mental health conditions and brain fog over time, preventive interventions and treatments are needed. Research is needed to explore underlying mechanisms that could inform further research in development of effective treatments. The reduced risk of brain fog associated with vaccination emphasizes the need for ongoing vaccination programs.
     
  3. Eleanor

    Eleanor Senior Member (Voting Rights)

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    Not convinced that lumping 'mental health conditions' and 'brain fog' together tells us much about either category of problem.
     
  4. rvallee

    rvallee Senior Member (Voting Rights)

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    Combining those make no sense. Even worse that most "mental health" is mostly misattribution of symptoms, always in one preferred direction even though it makes the least sense. Especially given the diminished prevalence from vaccination, which clearly points to immunological factors where psychology is irrelevant other than as a consequence, and something where health care tends to do far more harm than good precisely because of weird nonsense like arbitrarily combining different things.

    Plus this isn't prevalence of either, it's only as good as what the studies evaluate, so a study of studies and what they choose to label, rather than what the patients actually experience. Some studies have absurdly reported little of either because of how they chose to evaluate, even though it's fair to say that there are psychological consequences in LC, it's just that they're, well, a consequence of LC, with a heap of overlapping questions that, hey almost like there's a pattern, combine different things together. What they recommend is like putting mosquito nets around a fire to trap the smoke under the misguided notion that it will extinguish the fire. Somehow.

    When the quality of studies isn't going up with time, there is a fundamental problem that has to be fixed. It's the same old nonsense that has sunk everything for decades, there's just more of it.
     

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