Trial Report Plasma cell targeting with the anti-CD38 antibody daratumumab in ME/CFS -a clinical pilot study, 2025, Fluge et al

[Jonathan Edwards]

OK thanks—and then after 3 months or so did their symptoms stabilize (flatten) or was there continued improvement in their symptoms over the following year plus as in the attached figures from the Fluge Dara paper?

Two relapsed at B cell repopulation at 6 months. Those that didn't either remained completely well or improved further to be well.

 

[Pibee]

I know this guy on Twitter, a Belgian ? I m pretty sure that he doesn’t have MECFS. He is not a good example.

Belgian Twitter guy is my best friend, I know him for 10 yrs, he has MECFS from SJogrens, it's one of symptoms he has PEM and he was very severe housebound for 10 yrs. I shared his steps recently on other forum. I don't know have they been posted here, I'll share again

Those who read any papers ever on Sjogrens know that it can cause MS, MG, CIDP, GBS, and a number of other neurological conditions like POTS and obviously PEM/MECFS.

 

[ryanc97]

Did you improve with the higher NK-cell count?

Why would I? There is no viral persistence. but no, whether my NK cells were 60 or 450 I felt literally the same.

 

[forestglip]

Several posts about Sjogren's were moved to: Is there a connection between ME/CFS and Sjogren's Syndrome? Discussion and a poll about testing