" Healthcare (Basel). 2018 Apr 14;6(2). pii: E33. doi: 10.3390/healthcare6020033. Persistent Borrelia Infection in Patients with Ongoing Symptoms of Lyme Disease. Middelveen MJ1, Sapi E2, Burke J3, Filush KR4, Franco A5, Fesler MC6, Stricker RB7. .... CONCLUSIONS: Using multiple corroborative detection methods, we showed that patients with persistent Lyme disease symptoms may have ongoing spirochetal infection despite antibiotic treatment, similar to findings in non-human primates. The optimal treatment for persistent Borrelia infection remains to be determined." Abstract on PubMed and full article. Please alert me if this article has been posted before. The result of this small study points to what many patients with Lyme , with or without ME/CFS, have suspected for years.