I am not surprised that nobody has found consistent physiological abnormalities in ME. It is quite difficult to work out what one would be looking for.
I wrote on the M. Tack thread that the finding of very low erythrocyte sedimentation rates--ESR (<3mm/hr) seems to be consistent and confirmed by 2018 Blood (Saha/Davis) paper. The problem (for the clinician and the patient and maybe the researcher) is that the diagnostic labs do not flag low ESR (it's super healthy!)--they only flag it when it is high. Physicians will never, ever notice/find anything on a lab test unless it is flagged as out of range by the lab.