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New sleeping sickness drug approved

Discussion in 'Other health news and research' started by Jaybee00, Nov 19, 2018.

  1. Jaybee00

    Jaybee00 Senior Member (Voting Rights)

    merylg, Kalliope, Inara and 7 others like this.
  2. Sly Saint

    Sly Saint Senior Member (Voting Rights)

    from Wikipedia
    Fexinidazole is an antiprotozoal agent.[1] It has activity against Trypanosoma cruzi, Tritrichomonas foetus, Trichomonas vaginalis, Entamoeba histolytica,[1] Trypanosoma brucei,[2] and Leishmania donovani.[3] The biologically relevant active metabolites in vivo are the sulfoxide and sulfone.[3][4] Fexinidazole was discovered by the German pharmaceutical company Hoechst AG, but its development as a pharmaceutical was halted in the 1980s.[5] Fexinidazole is now being studied through a collaboration between Sanofi and the Drugs for Neglected Diseases Initiative for the treatment of Chagas disease and human African trypanosomiasis (sleeping sickness).[6][7] Fexinidazole is the first drug candidate for the treatment of advanced-stage sleeping sickness in thirty years.[8]

    @Retha Viviers

    merylg, MEMarge, hinterland and 3 others like this.
  3. Kalliope

    Kalliope Senior Member (Voting Rights)

    Is this in any way similar to Suramin or something completely different?
    andypants, Perrier, MEMarge and 3 others like this.

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