Or at least easier to point out.
Getting it taken into account and acted on is another matter entirely. As we have learned the hard way.
And data.
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Metaresearch on patient-reported outcomes in trial protocols and results publications suggested large outcome reporting bias, 2025, Heravi, Busse et
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Getting it taken into account and acted on is another matter entirely. As we have learned the hard way.
There are things that could be done to improve PRO inclusions, such as reporting what % of participants fully filled out the questionnaire. A low number might indicate selection bias (or fatalities, or "too sick to fill out a form"). Whichever improvements are in the guidelines, the problem lies in motivating people to follow them properly, and in dealing with the people who find ways to abuse them. Guidelines may work for ethical people, but they're not the problem the guidelines are meant to solve.