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Medscape: More Evidence Anticholinergic Meds Boost Dementia Risk

Discussion in 'Health News and Research unrelated to ME/CFS' started by Andy, May 6, 2018.

  1. Andy

    Andy Committee Member (& Outreach when energy allows)

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    Location:
    Hampshire, UK
    https://www.medscape.com/viewarticle/896005
     
    Indigophoton, Trish, Aroa and 9 others like this.
  2. Esther12

    Esther12 Senior Member (Voting Rights)

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    4,126
    I know amitriptyline gets recommended to help with migraines, pain and sleep problems, all things that can be an issue with ME/CFS.
     
  3. Little Bluestem

    Little Bluestem Senior Member (Voting Rights)

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    1,450
    At one time, depression was the #1 misdiagnosis for ME/CFS. I'll bet a lot of us old-timers have been on anti-depressants. :(
     
  4. Inara

    Inara Senior Member (Voting Rights)

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    2,725
    There was a previous study about this in 2015: https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2091745?resultClick=3
    This new study works with larger numbers (around 40.000 patients and 280.000 controls).

    Anticholinergic drugs are also "First generation antihistamines like diphenhydramine (Benadryl) and chlorpheniramine (Chlor-Trimeton). Drugs with diphenhydramine are also often taken as a sleep aid." (https://wa-health.kaiserpermanente.org/antihistamine-increase-risk-dementia/)

    Here, some anticholinergic drugs are listed:
    https://www.theseniorlist.com/list-of-anticholinergic-drugs/

    From the paper cited in the medscape articke:
    The authors of this study say:
     

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