Linking infections with autoimmune disease + modified virus discover new autoantibodies

Discussion in 'Research methodology news and research' started by FMMM1, Apr 22, 2024.

  1. FMMM1

    FMMM1 Senior Member (Voting Rights)

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    Article here* noticed that they use engineered virus to look for autoantibodies - similar to the approach of the group at Yale [Aaron Ring etc. using genetically modified fungi to produce target protein].
    From the press article -
    "They took a technique in which viruses are engineered to display bits of proteins like flags on their surface, called phage display immunoprecipitation sequencing (PhIP-Seq), and further optimized it to screen human blood for autoantibodies."



    *
    Signs of Multiple Sclerosis Show Up in Blood Years Before Symptoms Appear
    https://www.ucsf.edu/news/2024/04/4...h,autoantibodies years before their diagnosis.
     

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