Has anybody used this medicine? Or any other allergy medicine for ME? I've been having insistent dull pain on my left flank for about 6 months. It's now bothering me full time. So, I went to an internist last Thursday. He examined me and felt that my intestines were very hard. I thought he was going to do a scan. But he said I need a colonoscopy which I already booked it for next month. I also mentioned all my allergic skin and GI problems, he had prescribed me Xyzal. This is my third day on it, the itch is lessened about 50% and the flank pain is less noticeable, but made me more fatigued than my usual ME fatigue. I slept more than 10 hours past two nights. The dr does not know ME and I've not mentioned it. I mentioned all my problems as separate symptoms and he said, he thought they are all related and possibly an auto immune problem causing allergies. He also prescribed a medicine for cramping and gas and a probiotic capsules. I've not used them yet, he said use them when in need. I'm not too bad for gas and bloating at the moment. Has anyone else use Xyzal? It kind of made me calmer and more normalish. It also surprisingly eased the pain and puffiness of my right ankle and gave me appetite. Any thoughts?