Lancet Respiratory Medicine: Post-acute Sequelae of COVID-19, 2023, series of research papers

[Sly Saint]

Published: July 17, 2023
Executive Summary


Many patients with COVID-19 develop physical, cognitive, and mental health impairments that persist for more than 3 months after infection, known collectively as long COVID or post-COVID-19 condition. Survivors of COVID-19-related critical illness are also at risk of the complications of post-intensive care syndrome. These multisystem manifestations can have a devastating impact on survivors and their families, with important implications for health-care systems and society.

In the first of a Series of three papers, Sally Singh and colleagues outline pulmonary and extrapulmonary origins of persistent breathlessness and consider the promise of adapted pulmonary rehabilitation programmes and physiotherapy techniques for breathing management. Pratik Pandharipande and colleagues discuss the mechanistic underpinnings of neurological, cognitive, and psychiatric sequelae of COVID-19-related critical illness and outline potential mitigation strategies. Finally, Matteo Parotto and colleagues discuss pathophysiological mechanisms of the multisystem manifestations of post-COVID-19 condition after critical illness, highlight the challenges of providing appropriate care and support for survivors, and outline priorities for research.

https://www.thelancet.com/series/post-acute-sequelae-of-COVID-19

 

[Lucibee]

Interesting series.

Here are the links to the individual papers.

Respiratory sequelae of COVID-19: pulmonary and extrapulmonary origins, and approaches to clinical care and rehabilitation
Sally J Singh, Molly M Baldwin, Enya Daynes, Rachael A Evans, Neil J Greening, R Gisli Jenkins, Nazir I Lone, Hamish McAuley, Puja Mehta, Joseph Newman, Petr Novotny, David J F Smith, Stefan Stanel, Mark Toshner, Christopher E Brightling
The Lancet Respiratory Medicine
Published online: May 19, 2023
https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(23)00159-5/fulltext

Mitigating neurological, cognitive, and psychiatric sequelae of COVID-19-related critical illness
Pratik Pandharipande, Shawniqua Williams Roberson, Fiona E Harrison, Jo Ellen Wilson, Julie A Bastarache, E Wesley Ely
The Lancet Respiratory Medicine
Published online: July 17, 2023
https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(23)00238-2/fulltext

Post-acute sequelae of COVID-19: understanding and addressing the burden of multisystem manifestations
Matteo Parotto, Mariann Gyöngyösi, Kathryn Howe, Sheila N Myatra, Otavio Ranzani, Manu Shankar-Hari, Margaret S Herridge
The Lancet Respiratory Medicine
Published online: July 17, 2023
https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(23)00239-4/fulltext

Comment
Long COVID - unravelling a complex condition
Carol L Hodgson, Tessa Broadley
The Lancet Respiratory Medicine
Published online: July 17, 2023
https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(23)00232-1/fulltext

Patient Perspectives
Long COVID? What is that?
Jules Morgan
The Lancet Respiratory Medicine, Vol. 11, No. 6, June 2023, p515-517
Published online: March 24, 2023
https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(23)00126-1/fulltext


So far, only one of these has appeared in print (the Patient Perspective).

Singh et al. invokes the deconditioning theory and recommends exercise therapy. No mention of ME/CFS.

However, both Pandharipande et al. and Parotto et al. mention similarities to ME/CFS.