Joint Hypermobility, autonomic hyperactivity: Relevance to neurodevelopmental disorders, 2014, Eccles et al.

Abstract conclusion:
Conclusion We demonstrate for the first time that rates of hypermobility and symptoms of autonomic dysfunction are particularly high in adults with neurodevelopmental diagnoses. It is likely that the importance of hypermobility and autonomic dysfunction to the generation and maintenance of psychopathology in neurodevelopmental disorders is poorly appreciated.

Work underway(autonomic testing, fMRI) will test the hypothesis that autonomic reactivity and interoceptive sensitivity predispose to the expression of psychiatric symptoms, particularly anxiety.

It is further hypothesized that inefficient neural co-ordination of efferent autonomic drive with imprecise interoceptive representations may be amplified in hypermobile individuals. In hypermobility, this mechanism might explain increased vulnerability to stress sensitive and developmental neuropsychiatric conditions.
 
There comes a point with this sort of research when you get what I think is called an 'embarras de richesse' - too many good things. If they end up finding that hypermobility is associated with every condition they study the likely conclusion is that they are not measuring hypermobility reliably. The great majority of people who research hypermobility do not measure it reliably so it would be no surprise.

The main concern here is that Neil Harrison is involved. He should know better than to put his name to flaky research. Maybe it will turn out not to be flaky but I sense a case of mille-feuille here.
 
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