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James P Allison and Tasuku Honjo win Nobel prize for medicine

Discussion in 'Health News and Research unrelated to ME/CFS' started by hinterland, Oct 1, 2018.

  1. hinterland

    hinterland Senior Member (Voting Rights)

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    Wessely, White and Sharpe overlooked again...


    PS: I’m not sure this work has any direct implications for ME/CFS, where, as I understand it, if anything, we’re trying to dampen down immune reactivity.
    Last edited: Oct 1, 2018
    Indigophoton, EzzieD, Andy and 11 others like this.
  2. TrixieStix

    TrixieStix Senior Member (Voting Rights)

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    This new WIRED article goes into much more detail about James Allison and his career and research from beginning to now. It's long, but quite interesting.

    Meet the Carousing, Harmonica-Playing Texan Who Just Won a Nobel for his Cancer Breakthrough

    "The war on cancer is not over; we have not achieved a full and total cure, and so far the handful of cancer immunotherapy drugs available have demonstrated robust and durable results in a minority of patients. But we have undeniably turned a corner in our understanding of the disease—what many scientists believe to be a “penicillin moment” in our quest for the cure.

    The CTLA-4-blocking drug Ipilumimab, approved by the FDA in 2015, was the first of a new class of drugs called “checkpoint inhibitors” and the beginning of what researchers refer to as a tsunami of new cancer treatments. The pace of progress is staggering, such that we now recognize that what Allison discovered is not only the end of that 100-year scientific mystery, but also the the beginning of a new chapter in medicine. Already, new therapies such as CAR-T have essentially wiped out some forms of cancer; the newest checkpoint inhibitors have turned stage-four metastatic death sentences into full remission. This work has only just begun. And while it’s hopeful, it’s not hype."

    Last edited: Oct 24, 2018
    Indigophoton, MEMarge, Inara and 6 others like this.

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