Does anyone have a reference to what an inverted CD4/CD8 ratio can indicate (0.7 to 0.8 consistently). Naive CD4 % is normal, but naive CD8 % is elevated. All other CD8 components (effector memory, etc. are low). I have only read that it indicates an “unstable” or impaired immune system, or can indicate “nervous system conditions” ( https://www.urmc.rochester.edu/encyclopedia/content.aspx?ContentTypeID=167&ContentID=cd4_cd8_ratio). I’d appreciate any information.