Individualized and Controlled Exercise Training Improves Fatigue and Exercise Capacity in Patients with Long-COVID, 2024, Kieffer et al.

Chandelier

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Individualized and Controlled Exercise Training Improves Fatigue and Exercise Capacity in Patients with Long-COVID

Kieffer, Simon; Krüger, Anna-Lena; Haiduk, Björn; Grau, Marijke

Abstract
Background
: Long-term health effects after SARS-CoV-2 infections can manifest in a plethora of symptoms, significantly impacting the quality of life of affected individuals.

Aim: The present paper aimed to assess the effects of an individualized and controlled exercise intervention on fatigue and exercise capacity among Long-COVID (LC) patients in an ambulatory setting.

Methods: Forty-one (n = 41) LC patients performed an exercise protocol with an individualized control of the patients’ training intensity during the study period based on the individual’s ability to achieve the target criteria. The program was carried out two to three times a week, each session lasted 30 min, and the study parameters were recorded at the beginning of the program, as well as after 6 and 12 weeks, respectively. These included both patient-reported (PCFS questionnaire, FACIT–Fatigue questionnaire) and objective (one-minute sit-to-stand test (1MSTST), workload) outcomes.

Results: The exercise training intervention resulted in significant improvements in the FACIT–Fatigue (F(2, 80) = 18.08, p < 0.001), 1MSTST (χ2(2) = 19.35, p < 0.001) and workload scores (χ2(2) = 62.27, p < 0.001), while the PCFS scores remained unchanged. Changes in the workload scores were dependent on the frequency of the completed exercise sessions and were higher in the LC patients with a moderate Post COVID Syndrome Score (PCS) compared to a severe PCS.

Conclusions: The individualized and controlled training approach demonstrated efficacy in reducing fatigue and enhancing exercise capacity among outpatient LC patients. However, for complete regeneration, a longer, possibly indefinite, treatment is required, which in practice would be feasible within the framework of legislation.

Web | DOI | PMC | PDF | Biomedicines
 
I'm posting this study from 2024 due to this news article from today proclaiming loudly that exercise at just the right dose is the key against Long Covid:

tldr: The wife of a senior physican at a german rehabilitation center got long covid. In his desperation he learns about a the tribal-therapy and buys a special training bike. As a perceived result of the training she feels a bit better (no further information was provided).
Edit: this seems to be the bike:
5512_M3I_TOTAL_BODY_TRAINER-Right_Side-cinv-1622232906434835.jpg


Short AI Summary:
  • Small Doses of Exercise: A study from the S.P.O.R.T. Institute shows that moderate physical activity can help treat Long-Covid, with careful monitoring to avoid relapse.
  • Tribal-Therapy: Participants use a special full-body exercise machine for 15-minute sessions, three times a week. Afterward, rest periods with stretching or mud treatments are incorporated.
  • Positive Results: Linda Sips, a Long-Covid patient, regained strength and endurance after starting Tribal-Therapy. She now requires fewer breaks and has resumed some daily activities.
  • Tailored Training: The intensity of exercise is adjusted based on continuous health data analysis. Overexertion is avoided to prevent setbacks.
  • Access & Duration: The therapy is available in multiple centers across Germany, and treatment is free for participants in Aachen. The program can last up to 1.5 years, though long-term effectiveness is still being studied.
Google translation
 
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No control group and plenty of room for natural recovery. The dose response relationship could be explained by the fact that the people that were bound to feel better naturally also were able to participate more.

Seems like a waste of time. Why not do a proper study for once?
 
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